Segmented biopolyurethanes for medical applications

Doina Macocinschi; Daniela Filip; Stelian Vlad; Mariana Cristea; Maria Butnaru

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Segmented biopolyurethanes for medical applications

机译：用于医疗用途的分段式生物聚氨酯

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Polyurethanes are one of the most popular groups of biomaterials applied for medical devices. Their segmented block copolymeric character endows them a wide range of versatility in terms of tailoring their physical properties, blood and tissue compatibility. Polyester- and polyether-urethanes have been modified with hydroxypro-pyl cellulose aiming the change of their surface and bulk characteristics to confer them biomaterial qualities. In this respect, dynamic contact angle measurements, dynamic mechanical analyses accompanied by mechanical testing have been done. Platelet adhesion test has been carried out in vitro and the use of hydroxypropyl cellulose in the polyurethane matrix reduces the platelet adhesion and therefore recommends them as candidates for biocompatible materials.

机译：聚氨酯是用于医疗设备的最受欢迎的生物材料之一。它们的嵌段嵌段共聚特性赋予了它们广泛的多功能性，可调整其物理性质，血液和组织的相容性。聚酯和聚醚氨基甲酸酯已经用羟丙基纤维素改性，旨在改变其表面和体积特性，赋予它们生物材料的品质。在这方面，已经进行了动态接触角测量，伴随机械测试的动态机械分析。血小板粘附性测试已在体外进行，在聚氨酯基质中使用羟丙基纤维素会降低血小板粘附性，因此建议将其用作生物相容性材料的候选者。

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《Journal of materials science》 |2009年第8期|1659-1668|共10页
作者
Doina Macocinschi; Daniela Filip; Stelian Vlad; Mariana Cristea; Maria Butnaru;
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作者单位

'Petru Poni' Institute of Macromolecular Chemistry, Iasi 700487, Romania;

'Petru Poni' Institute of Macromolecular Chemistry, Iasi 700487, Romania;

'Petru Poni' Institute of Macromolecular Chemistry, Iasi 700487, Romania;

'Petru Poni' Institute of Macromolecular Chemistry, Iasi 700487, Romania;

Faculty of Medical Bioengineering, 'Gr. T. Popa' University of Medicine and Pharmacy, Iasi 700115, Romania;

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Segmented biopolyurethanes for medical applications

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