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首页> 外文期刊>Journal of Medical Colleges of PLA >Epidemiological and pathogenic study on the outbreak of toxic shock syndrome and meningocephalitis caused by swine streptococcus
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Epidemiological and pathogenic study on the outbreak of toxic shock syndrome and meningocephalitis caused by swine streptococcus

机译：猪链球菌引起的中毒性休克综合征和脑膜脑炎的流行病学和致病性研究

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Objective: To reveal the relationship between the biological characteristics of pathogen and the pig- to- human spread of the epidemic and infectious disease in 1998 in East China. Methods: Epidemiological survey, pathological examination of pigs and patients, and pathogen isolation were performed. Results: The disease had a character of quick onset, serious symptoms, short course and high mortality. The clinical manifestations and pathological changes of the disease were high fever, sometimes with nausea, vomiting and diarrhea, then might develop to myositis, fascitis, DIC, multiple organ failure, shock and usually died in 2-3 d. Among 25 patients, 16 manifested clinically as streptococcal toxic shock syndromes and 9 streptococcal meningiocephalitis syndrome. The mortality was 81.25% and 11.11% respectively. Pathogenic bacteria isolated from diseased pigs and patients were found to have some common characteristics in morphology, staining and biological characters. Conclusion: The pathogen isolated from the blood of patients and pigs were identified as streptococci.
机译：目的：揭示1998年华东地区病原菌的生物学特性与猪和人间流行病和传染病传播的关系。方法：进行流行病学调查，猪和病人的病理检查以及病原体分离。结果：该病起病快，症状严重，病程短，死亡率高。该病的临床表现和病理变化为高烧，有时伴有恶心，呕吐和腹泻，然后可能发展为肌炎，筋膜炎，DIC，多器官功能衰竭，休克，通常在2-3 d内死亡。在25例患者中，有16例临床表现为链球菌中毒性休克综合征，还有9例为链球菌脑膜脑炎综合征。死亡率分别为81.25％和11.11％。从患病猪和患者身上分离出的病原菌在形态，染色和生物学特性方面具有一些共同特征。结论：从患者和猪血中分离出的病原体被鉴定为链球菌。

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