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Studies on the Antibacterial Activity of the Extract of Stachytarpheta angustifolia

机译:水飞蓟提取物的抑菌活性研究

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Objective: To investigate the scientific bases far the traditional use of Stachy-tarpheta angusti folia. Methods: In vitro antibacterial activity of the aqueous and ethanol extract of the plant was investigated using the agar cup plate diffusion method. Results: The ethanol extract of the plant showed antibacterial activity against Escherichia coli, Streptococcus faecalis, Shigella dysenteriae, Staphylococcus aureus (S. aureus), Salmonella sp. , Pseudomonas aeruginosa and Neisseria gonar-rhoeae, while the water extract was active against Escherichia coli, Streptococcus faecalis, Shigella dysenteriae, Staphylococcus aureus and. Pseudomonas aeruginosa. The ethanol extract exhibited higher antibacterial activity than the water extract. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the ethanol extract were 0. 65 mg/ml and 0. 85 mg/ml, respectively, against S. aureus. Treatment of the extract at higher temperature, 60 C increased the sensitivity of the test organisms to the plant extract. Phytochemical analysis indicated that the plant possesses tannins, saponins as well as phenols. Conclusion: A scientific basis exists that the plant possesses antibacterial activity and it could be a probable source of therapeutic agent.
机译:目的:探讨远古水苏传统用法的科学依据。方法:采用琼脂杯平板扩散法研究了水和乙醇提取物的体外抗菌活性。结果:该植物的乙醇提取物对大肠杆菌,粪链球菌,痢疾志贺氏菌,金黄色葡萄球菌(S. aureus),沙门氏菌等具有抗菌活性。 ,铜绿假单胞菌和淋病奈瑟氏球菌,而水提取物对大肠杆菌,粪便链球菌,痢疾志贺氏菌,金黄色葡萄球菌和。铜绿假单胞菌。乙醇提取物表现出比水提取物更高的抗菌活性。乙醇提取物对金黄色葡萄球菌的最小抑菌浓度(MIC)和最小杀菌浓度(MBC)分别为0. 65 mg / ml和0. 85 mg / ml。在更高的温度(60℃)下处理提取物可提高测试生物对植物提取物的敏感性。植物化学分析表明,该植物具有单宁,皂角苷和酚类。结论:该植物具有抗菌活性,并且可能是治疗药物的可能来源,具有科学依据。

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