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首页> 外文期刊>Journal of nano research >The Effect of Curcumin Against in vitro Adhesion of Implant Device-associated Bacteria on Nanosized Titanium Dioxide
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The Effect of Curcumin Against in vitro Adhesion of Implant Device-associated Bacteria on Nanosized Titanium Dioxide

机译：姜黄素对植入装置相关细菌体外粘附纳米二氧化钛的影响

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摘要

Although titanium dioxide (TiO_2) is an implantable biomaterial with its antibacterial activity, infection on TiO_2 surfaces remains a problem for medical settings. According to our previous studies, curcumin, the main component of turmeric (Curcuma longa), partially hindered the attachment of Streptococcus mutans to human tooth surfaces. Therefore, it was examined whether several implant device-associated bacteria were able to adhere to nanosized TiO_2 surfaces. In addition, the effect of curcumin on the bacterial adhesion was investigated. Bacterial strains were cultured on pure Ti and TiO_2 surfaces with various nanotube sizes in the absence or presence of curcumin and observed by scanning electron microscopy. Consequently, most bacteria adhered to Ti and TiO_2 surfaces. However, curcumin increased the adhesion of bacteria including S. mutans. The results suggest that bacterial adhesion to implant titanium surfaces can be augmented via curcumin ingestion.
机译：尽管二氧化钛（TiO_2）是具有抗菌活性的可植入生物材料，但是TiO_2表面的感染仍然是医疗环境中的问题。根据我们之前的研究，姜黄素是姜黄的主要成分（姜黄），部分阻碍了变形链球菌附着在人牙齿上。因此，检查了几种与植入装置相关的细菌是否能够附着在纳米TiO_2表面上。此外，研究了姜黄素对细菌粘附的影响。在没有或没有姜黄素的情况下，将细菌菌株培养在具有各种纳米管尺寸的纯Ti和TiO_2表面上，并通过扫描电子显微镜观察。因此，大多数细菌粘附在Ti和TiO_2表面上。但是，姜黄素增加了包括变形链球菌在内的细菌的粘附力。结果表明，可以通过摄取姜黄素来增强细菌对植入钛表面的粘附力。

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  • 来源
    《Journal of nano research》 |2013年第2013期|83-90|共8页
  • 作者

    Seunghan Oh; In-Young Na; Kyoung-Hee Choi;

  • 作者单位

    Department of Dental Biomaterials, College of Dentistry, Wonkwang University, Iksan, Chonbuk 570-749, Korea,Institute of Biomaterials-lmplant, Wonkwang University, Iksan, Chonbuk 570-749, Korea;

    Department of Life Science, Wonkwang University, Iksan, Chonbuk 570-749, Korea;

    Department of Oral Microbiology, College of Dentistry, Wonkwang University, Iksan, Chonbuk 570-749, Korea,Institute of Biomaterials-lmplant, Wonkwang University, Iksan, Chonbuk 570-749, Korea;

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  • 正文语种 eng
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  • 关键词

    nanotubes; titanium dioxide; Streptococcus mutans; bacterial adhesion; curcumin;

    机译：纳米管二氧化钛;变形链球菌;细菌粘附姜黄素;

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