Observations on the Vietnam Palo Alto Strain of Plasmodium vivax in Two Species of Aotus Monkeys

William E. Collinsa JoAnn S. Sullivana G. Gale Gallanda Allison Williamsa Douglas Nacea Tyrone Williams*b and John W. Barnwella

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Observations on the Vietnam Palo Alto Strain of Plasmodium vivax in Two Species of Aotus Monkeys

机译：越南帕洛阿尔托疟原虫在两种Two猴中的观察。

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Thirty-three splenectomized Aotus lemurinus griseimembra monkeys with no previous experience with malaria were infected with the Vietnam Palo Alto strain of Plasmodium vivax. The median maximum parasite count was 280,000/μl. Nine splenectomized monkeys with previous infection with Plasmodium falciparum had median maximum parasite counts of 120,000/μl. Splenectomized Aotus nancymai monkeys supported infections at a lower level. Transmission via the bites of Anopheles dirus mosquitoes was obtained in a splenectomized A. lemurinus griseimembra, with a prepatent period of 31 days. It is estimated that between 1.5 × 108 and 1.6 × 109 parasites can be removed from an infected animal for molecular or diagnostic antigenic studies.

机译：33例没有疟疾经验的脾切除的Aotus lemurinus griseimembra猴子感染了越南Palo Alto间日疟原虫菌株。中位数最大寄生虫计数为280,000 /μl。先前感染过恶性疟原虫的九只脾脏切除的猴子中位最大寄生虫计数为120,000 /μl。脾脏切除的南猿猴支持较低水平的感染。通过脾脏切除的A. lemurinus griseimembra获得了经蚊按蚊叮咬的传播，有效期为31天。据估计，可以从被感染的动物中去除1.5×108至1.6×109个寄生虫，以进行分子或诊断性抗原研究。

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《Journal of Parasitology》 |2005年第2期|p.00000461-00000463|共3页
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William E. Collinsa JoAnn S. Sullivana G. Gale Gallanda Allison Williamsa Douglas Nacea Tyrone Williams*b and John W. Barnwella;
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aDivision of Parasitic Diseases and Animal Resources Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, 30341. wec1@cdc.gov bAtlanta Research and Education Foundation, Atlanta, Georgia 30333;

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2. The Chesson strain of plasmodium vivax in humans and different species of Aotus monkeys. [J] . Collins WE, Sullivan JS, Jeffery GM The American Journal of Tropical Medicine and Hygiene . 2009,第1期

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Observations on the Vietnam Palo Alto Strain of Plasmodium vivax in Two Species of Aotus Monkeys

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