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Layer by Layer Photo-Cross-Linked Environmental Functional hydrogel Thin Films Based on Vanillin: Part 3

机译:层由层光交联的环形功能水凝胶薄膜基于香草林:第3部分

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The present work emphasizes the preparation of new monomer from the family of vanillin acrylate. It has been prepared in two steps the name of the final product is [2-((ditert-butylamino) methyl)-4-formyl-6-methoxyphenyl acrylate] and abbreviated by TBAMVA, both products were evaluated by H-1, C-13 NMR and FTIR and they were in the logic case with the chemical structure. The next step was the preparation of three different pH and temperature responsive copolymers by free radical polymerization of 5, 10, 20mol% of TBAMVA and 5mol% of maleimide photo-cross-linker with N-isopropylacrylamide. Polymers were chemically and physically characterized indicating the presence of the aldehyde group in the main chain. The lower critical solution temperature of polymers has been determined by two methods; the first one using turbidity measurements by UV-Vis Spectroscopy, another method using micro-DSC. The last step was the formation of pH-Temperature responsive hydrogel layer over gold and studying the swelling properties response to pH and temperature using surface plasmon resonance with the optical waveguide. In the present work, we focused on synthesizing new environmental functional polymers and hydrogel thin films used as biosensor as a target for many biological molecules in biosynthesis, drug delivery, and bio-separation.
机译:目前的工作强调了从香草蛋白丙烯酸酯家族的新单体的制备。它已在两个步骤中制备最终产物的名称是[2 - ((二叔丁基氨基)甲基)-4-甲酰基-6-甲氧基苯基丙烯酸酯]并由TBAMVA缩写,两种产品由H-1,C评估-13 NMR和FTIR,它们在具有化学结构的逻辑盒中。下一步骤是通过自由基聚合制备三种不同的pH和温度响应共聚物5,10,20mol%的TBAMVA和5mol%的马来酰亚胺光交联剂与N-异丙基丙烯酰胺。聚合物化学和物理表征表明主链中存在醛基。聚合物的较低临界溶液温度已通过两种方法确定;第一个使用UV-VIS光谱法测量浊度测量,另一种使用Micro-DSC的方法。最后一步是在金色上形成pH-温度响应水凝胶层,并使用光波导的表面等离子体共振来研究对pH和温度的溶胀性能。在本作工作中,我们专注于合成使用用作生物传感器的新的环形功能聚合物和水凝胶薄膜作为生物合成,药物递送和生物分离中许多生物分子的靶标。

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