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首页> 外文期刊>Journal of Polymers and the Environment >Preparation as Well as Evaluation of the Nanofiber Membrane Loaded with Nigella sativa Extract Using the Electrospinning Method
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Preparation as Well as Evaluation of the Nanofiber Membrane Loaded with Nigella sativa Extract Using the Electrospinning Method

机译：使用静电纺丝法制备纳米纤维膜的纳米纤维膜的评价

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摘要

In the present study, the edible and biodegradable Zein microfiber is prepared using the glacial acetic acid solvent and electrospinning approach. It is possible to produce uniform nanofibers without bead by changing several parameters such as the concentrations of Zein and drug, gap between the needle tip and collector, electrospinning voltage and solution's flow rate. Here, the solution of Zein and black seed (Nigella sativa) oil has been produced and electrospun at three different oil concentrations of 5, 10 and 15% w/v. The electrospinning voltage, gap between the needle tip and collector and flow rate were kept fixed for these three concentration levels as 20 kV, 15 cm and 4 mL/h, respectively. According to the obtained results, the concentration variation of the black seed oil has a significant effect (P = 0.05) on the fiber diameter in such a way that fiber diameter increases with an increment in the oil concentration. Further aim of the present study is to prepare as well as evaluate the membrane properties of Zein nanofibers containing black seed oil using the electrospinning method for modern drug delivery uses.
机译：在本研究中，使用冰醋酸溶剂和静电纺丝方法制备可食用和可生物降解的Zein微纤维。通过改变诸如玉米蛋白和药物浓度的少数参数，针尖和集电极之间的间隙，静电纺丝电压和溶液的流速，可以通过改变诸如玉米蛋白和药物的浓度，间隙而没有珠子生产均匀的纳米纤维。这里，在5,10和15％w / v的三种不同的油浓度下制造和纺织纺织溶液的溶液。针尖和集电极之间的静电纺丝电压，与该三个浓度水平分别保持固定为20kV，15cm和4mL / h的固定。根据得到的结果，黑色种子油的浓度变化在纤维直径上具有显着影响（P <= 0.05），使得纤维直径随着油浓度的增量而增加。本研究的进一步目的是使用静电纺丝方法进行准备，评价含有黑色种子油的玉米醇蛋白纳面纤维的膜性能。

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