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首页> 外文期刊>Journal of Polymers and the Environment >Silver Nanoparticle Embedded alpha-Chitin Nanocomposite for Enhanced Antimicrobial and Mosquito Larvicidal Activity
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Silver Nanoparticle Embedded alpha-Chitin Nanocomposite for Enhanced Antimicrobial and Mosquito Larvicidal Activity

机译：银纳米粒子嵌入的α-甲壳素纳米复合材料，具有增强的抗菌和驱蚊灭蚊活性。

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摘要

Advent of nanotechnology opens up potential avenues for overcoming various challenges that includes control and cure of infectious diseases. The present study is focused on the synthesis of alpha-chitin nanoparticles (CNP) from the shells of Penaeus monodon Fabricius, silver nanoparticles (AgNP) and alpha-chitin/silver nanocomposite (CNP/AgNP), and to evaluate their antimicrobial and mosquito larvicidal activities. The antibacterial and antifungal activities are assessed against five different bacterial and fungal strains. Also the mosquito larvicidal potential is studied against Aedes aegypti a potential vector for malaria and dengue fever. The synthesized nanocomposites are characterized using UV-Vis spectroscopy, X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscope, energy-dispersive X-ray spectroscopy, transmission electron microscope and dynamic light scattering analysis. The antibacterial and antifungal assays reveal that the CNP/AgNP has an enhanced antimicrobial effect on inhibition of bacteria (P. vulgaris, K. pneumonia and S. aureus) as well as fungi (C. albicans, T. viridae, A. niger and A. alternate). Mosquito larvicidal assays confirm that CNP/AgNP has shown lowest LC50 and LC90 values than CNP and AgNP against all the instars of A. aegypti. Hence our result suggests that the incorporation of AgNP with CNP could improve the antimicrobial and mosquito larvicidal activity and have the potential to be used as biocompatible antimicrobial and mosquito larvicidal material.
机译：纳米技术的出现为克服各种挑战提供了潜在的途径，包括控制和治愈传染病。本研究的重点是从斑节对虾，银纳米颗粒（AgNP）和甲壳质/银纳米复合材料（CNP / AgNP）的壳中合成α-几丁质纳米颗粒（CNP），并评估它们的抗菌和灭蚊幼虫活动。针对五种不同的细菌和真菌菌株评估了抗菌和抗真菌活性。还针对埃及伊蚊（Aedes aegypti）（一种疟疾和登革热的潜在媒介）研究了蚊子幼虫的潜力。利用UV-Vis光谱，X射线衍射，傅立叶变换红外光谱，扫描电子显微镜，能量色散X射线光谱，透射电子显微镜和动态光散射分析对合成的纳米复合材料进行表征。抗菌和抗真菌分析表明，CNP / AgNP对细菌（寻常型毕赤酵母，肺炎克雷伯氏菌和金黄色葡萄球菌）以及真菌（白色念珠菌，绿假丝酵母，黑曲霉和细菌）的抑制作用增强。 A.替代）。蚊虫幼虫试验证实，针对埃及伊蚊的所有幼虫，CNP / AgNP的最低LC50和LC90值均低于CNP和AgNP。因此，我们的结果表明，AgNP与CNP的结合可以改善抗菌和灭蚊幼虫的活性，并有潜力用作生物相容性抗菌和灭蚊幼虫的材料。

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