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Chitin and Chitosan: Structure, Properties and Applications in Biomedical Engineering

机译:甲壳素和壳聚糖:结构,性质和在生物医学工程中的应用

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摘要

Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed beta-(1-4)-linked d-glucosamine (deacetylated unit) and N-acetyl-d-glucosamine (acetylated unit). Biopolymers like chitin and chitosan exhibit diverse properties that open up a wide-ranging of applications in various sectors especially in biomedical science. The latest advances in the biomedical research are important emerging trends that hold a great promise in wound-healing management products. Chitin and chitosan are considered as useful biocompatible materials to be used in a medical device to treat, augment or replace any tissue, organ, or function of the body. A body of recent studies suggests that chitosan and its derivatives are promising candidates for supporting materials in tissue engineering applications. This review article is mainly focused on the contemporary research on chitin and chitosan towards their applications in numerous biomedical fields namely tissue engineering, artificial kidney, skin, bone, cartilage, liver, nerve, tendon, wound-healing, burn treatment and some other useful purposes.
机译:几丁质及其脱乙酰基壳聚糖是天然聚合物,由无规分布的β-(1-4)连接的d-葡萄糖胺(脱乙酰基单元)和N-乙酰基-d-葡萄糖胺(乙酰化单元)组成。几丁质和壳聚糖等生物聚合物表现出多种多样的特性,从而打开了在各个领域的广泛应用,尤其是在生物医学领域。生物医学研究的最新进展是重要的新兴趋势,在伤口愈合管理产品中具有广阔的前景。几丁质和壳聚糖被认为是有用的生物相容性材料,可用于医疗设备中以治疗,增强或替代身体的任何组织,器官或功能。最近的大量研究表明,壳聚糖及其衍生物是在组织工程应用中支持材料的有希望的候选者。这篇综述文章主要针对几丁质和壳聚糖的当代研究,以探讨它们在众多生物医学领域中的应用,例如组织工程,人造肾脏,皮肤,骨骼,软骨,肝脏,神经,肌腱,伤口愈合,烧伤治疗以及其他一些有用的领域目的。

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