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X-ray technique for visualization of the bolus flow through an esophageal simulator

机译:用于通过食管模拟器可视化推注流动的X射线技术

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摘要

In the last years, there has been an interest in development of simulators to reproduce the mechanical properties of the human digestive system. Particularly, there have been some approaches in the development of esophagus simulators. Such simulators intend to replicate the peristaltic wave conditions, but the reported experiments are related to indirect measurements in which the use of a fluid is not reported. In this work, an X-ray technique for visualizing the flow of bolus through an artificial esophageal simulator (AES) is proposed. For that purpose, particles of barium sulfate were thoroughly mixed with baby food, in order to create a suspension used as bolus. Barium sulfate particles used in the present work are insoluble in water with non-regular forms, a size distribution from 20 to 80 nm, and a specific surface area ranging from 10 to 50 m~2/g. The advantage of using barium sulfate is its high absorption of X-rays, which allows obtaining a good contrast in radiographies, so that the transport of the bolus along the esophagus simulator can be easily tracked. The results revealed the appearance of secondary flows on the wave sides, which displace as the wave contracts. This was verified with the flow fields, in which it was observed that the bolus flows mainly along the central part of the wave and a small volume tends to retract. This confirms that the flow is extensional as the bolus is stretched and compressed during the peristalsis.
机译:在过去几年中,对模拟器的发展有兴趣再现人体消化系统的机械性能。特别是,在食道模拟器的开发中存在一些方法。这种模拟器旨在复制蠕动波条件,但报道的实验与间接测量有关,其中没有报道流体的使用。在这项工作中,提出了一种用于通过人造食管模拟器(AES)可视化推注流动的X射线技术。为此目的,硫酸钡颗粒与婴儿食品彻底混合,以产生用作推注的悬浮液。本作本作中使用的硫酸钡颗粒在具有非规则形式的水中不溶于水,尺寸分布为20至80nm,比10至50m〜2 / g的比表面积。使用硫酸钡的优点是其高吸收X射线,这允许在射线摄影中获得良好的对比度,从而可以容易地跟踪沿着食道模拟器的推注的运输。结果表明,波边的二次流动的外观,作为波浪合同移动。通过流场验证,其中观察到推注流出主要沿波的中心部分,并且小体积倾向于缩回。这证实了由于推注在蠕动期间被拉伸和压缩,因此流动是延伸的。

著录项

  • 来源
    《Journal of visualization》 |2021年第4期|761-769|共9页
  • 作者单位

    Instituto de Ciencias Aplicadas y Tecnologia Universidad Nacional Autonoma de Mexico 04510 Mexico City Mexico National Laboratory for Additive and Digital Manufacturing MADiT Mexico City Mexico;

    Facultad de Ingenieria Universidad Nacional Autonoma 04510 Mexico City Mexico;

    Instituto de Ciencias Aplicadas y Tecnologia Universidad Nacional Autonoma de Mexico 04510 Mexico City Mexico National Laboratory for Additive and Digital Manufacturing MADiT Mexico City Mexico;

    Institute of Theoretical and Applied Mechanics of the Czech Academy of Sciences Prosecka 809/76 Praha 9 190 00 Czech Republic;

    Instituto de Ciencias Aplicadas y Tecnologia Universidad Nacional Autonoma de Mexico 04510 Mexico City Mexico National Laboratory for Additive and Digital Manufacturing MADiT Mexico City Mexico;

    Instituto de Ciencias Aplicadas y Tecnologia Universidad Nacional Autonoma de Mexico 04510 Mexico City Mexico National Laboratory for Additive and Digital Manufacturing MADiT Mexico City Mexico;

    Fresenius-Kabi Deutschland GmbH 61352 Bad Homburg Germany;

    Instituto de Ciencias Aplicadas y Tecnologia Universidad Nacional Autonoma de Mexico 04510 Mexico City Mexico;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    Soft actuator; Esophageal simulator; Swallowing; Flow visualization; X-ray computed tomography; Biofluid mechanics;

    机译:软执行器;食管模拟器;吞咽;流动可视化;X射线计算断层扫描;生物流体力学;

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