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首页> 外文期刊>Journal of water and health >Chlorine inactivation of hepatitis E virus and human adenovirus 2 in water
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Chlorine inactivation of hepatitis E virus and human adenovirus 2 in water

机译：水中戊型肝炎病毒和人类腺病毒2的氯失活

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摘要

Hepatitis E virus (HEV) is transmitted via the fecal-oral route and has been recognized as a common source of large waterborne outbreaks involving contaminated water in developing countries. Thus, there is the need to produce experimental data on the disinfection kinetics of HEV by chlorine in water samples with diverse levels of fecal contamination. Here, the inactivation of HEV and human adenovirus C serotype 2 (HAdV2), used as a reference virus, was monitored using immunofluorescence and quantitative reverse transcription polymerase chain reaction (RT-qPCR) assays. HEV has been shown to be susceptible to chlorine disinfection and presented equivalent kinetics to human adenoviruses. The C(t) values observed for a 2-log reduction of HEV were 0.41 in buffered demand-free water and 11.21 mg/L × min in the presence of 1% sewage. The results indicate that the inactivation kinetics of HEV and HAdV2 are equivalent and support the use of chlorine disinfection as an effective strategy to control HEV waterborne transmission.
机译：戊型肝炎病毒（HEV）通过粪便-口途径传播，并已被认为是发展中国家涉及污染水的大规模水源性疾病暴发的常见来源。因此，需要产生有关粪便污染程度不同的水样中的氯对戊型肝炎病毒的消毒动力学的实验数据。在这里，使用免疫荧光和定量逆转录聚合酶链反应（RT-qPCR）分析监测用作参考病毒的HEV和人类腺病毒C血清型2（HAdV2）的失活。 HEV已显示对氯消毒敏感，并表现出与人腺病毒同等的动力学。在缓冲的无需求水中，HEV降低2个对数时所观察到的C（t）值为0.41，在有1％污水的情况下为11.21 mg / L×min。结果表明，HEV和HAdV2的失活动力学相当，并支持使用氯消毒作为控制HEV水性传播的有效策略。

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  • 来源
    《Journal of water and health》 |2014年第3期|436-442|共7页
  • 作者

    Rosina Girones; Anna Carratala; Byron Calgua; Miquel Calvo; Jesus Rodriguez-Manzano; Suzanne Emerson;

  • 作者单位

    Department of Microbiology, Faculty of Biology, University of Barcelona, Avd. Diagonal 643, Barcelona, 08028, Catalonia, Spain,Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8009, USA;

    Department of Microbiology, Faculty of Biology, University of Barcelona, Avd. Diagonal 643, Barcelona, 08028, Catalonia, Spain,Laboratory of Environmental Chemistry, School of Architecture, Civil and Environmental Engineering (ENAC), Ecole Polytechnique Federale de Lausanne, Lausanne 1015, Switzerland;

    Department of Microbiology, Faculty of Biology, University of Barcelona, Avd. Diagonal 643, Barcelona, 08028, Catalonia, Spain;

    Department of Biostatistics, University of Barcelona, Barcelona, 08028, Spain;

    Department of Microbiology, Faculty of Biology, University of Barcelona, Avd. Diagonal 643, Barcelona, 08028, Catalonia, Spain;

    Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-8009, USA;

  • 收录信息 美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    chlorine; disinfection; HAdV 2; HEV; sewage; water;

    机译：氯;消毒;HADV 2;混合动力车污水水;

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