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Histologic and Radiographic Evaluation of Progressive Loading on Implants Placed Into Extraction Sockets

机译：组织学和放射学评估渐进负荷在植入拔牙窝的植入物上

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摘要

To evaluate the effects of progressive loading on implants placed into extraction sockets. 4 beagle dogs were extracted bilateral 3rd, 4th and 2nd premolar and immediately inserted the implant at first surgery (0d), 14d and 21d. Using the newly developed vertical occlusion loading system, progressive loading procedures were taken 24h after insertion. The vertical bone loss (VBL) and bone-to-implant contact ratio (BIC) was measured by image analysis software and analyzed using the paired student t test. After 28d period of healing, each animal was sacrificed and the samples were evaluated by scanning electron microscopy (SEM). The mean vertical bone loss in control groups was larger than that of the experimental groups at 14, 21 and 28 day (P < 0.05). SEM showed that the mineralization rate of experimental groups was faster than the control groups. The bone-implant contact ratios in experimental groups were more than that in the control groups. The differences were statistically significant (P < 0.05). Compared with non-loading implant, progressive loading can promote osseointegration and decrease vertical bone loss. Progressive loading of implants placed into extraction sockets can be performed without interfering with the osseointegration process.
机译：评估渐进负荷对放置在拔牙窝中的植入物的影响。在第3、4和2前磨牙双侧拔出4只比格犬，并在第一次手术（0d），14d和21d立即插入植入物。使用新开发的垂直咬合加载系统，在插入后24小时采取渐进式加载程序。垂直骨丢失（VBL）和骨与植入物的接触比（BIC）通过图像分析软件进行测量，并使用配对学生t检验进行分析。愈合28天后，处死每只动物，并通过扫描电子显微镜（SEM）评估样品。对照组在第14、21和28天的平均垂直骨丢失量大于实验组（P <0.05）。扫描电镜显示，实验组的矿化速率快于对照组。实验组的骨-植入物接触率高于对照组。差异具有统计学意义（P <0.05）。与无负荷植入物相比，渐进负荷可促进骨整合并减少垂直骨丢失。可以在不干扰骨整合过程的情况下，逐步放置植入拔牙窝的植入物。

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