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In Vivo Comparison of Two Injectable Calcium Phosphate Biomaterials: Ionic Cement and Polymer-Associated Particulate Ceramic

机译:两种可注射磷酸钙生物材料的体内比较:离子水泥和聚合物缔合的颗粒陶瓷

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摘要

The present study compared the in vivo behavior of an ionic calcium phosphate bone cement and an composite injectable bone substitute (IBS) associating a biphasic calcium phosphate (BCP) mineral Phase and a cellulosic polymer. Three weeks after implantation in rabbit bone, both biomaterials expressed biocompatibility and bioactivity but new bone formation and ceramic degradadation were significantly higher for IBS than for than for the tested ionic cement. With IBS, newly-formed bone developed joining the BCP particles the ones to the others Whereas new bone only grew on the surface of the cement that remained dense with no Obvious degradation 3 weeks after implantation.
机译:本研究比较了离子磷酸钙骨水泥和将双相磷酸钙(BCP)矿物相与纤维素聚合物结合的复合可注射骨替代品(IBS)的体内行为。植入兔骨后三周,两种生物材料均表现出生物相容性和生物活性,但IBS的新骨形成和陶瓷降解显着高于被测试的离子水泥。借助IBS,新形成的骨骼得以发展,将BCP颗粒彼此连接在一起,而新的骨骼仅生长在粘固的水泥表面上,植入后3周没有明显降解。

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