...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Journal of biomedical materials research. Part B, Applied biomaterials. >In vivo behavior of a novel injectable calcium phosphate cement compared with two other commercially available calcium phosphate cements.
【24h】

In vivo behavior of a novel injectable calcium phosphate cement compared with two other commercially available calcium phosphate cements.

机译：与其他两种市售磷酸钙水泥相比，新型可注射磷酸钙水泥的体内行为。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The aim of this study was to investigate the physicochemical and biological properties of a newly developed calcium phosphate cement (CPC). The novel cement was compared with two other commercially available CPCs. After mixing the powder and liquid phase, the CPCs were injected as a paste into a rabbit distal femoral defect model. The CPCs were evaluated after 24 h, 6 weeks, 26 weeks, and 52 weeks. The novel CPC was easy to handle and was fast setting. X-ray diffraction (XRD) and Fourier Transform Infrared Spectrometry (FTIR) at the different implantation periods showed that the cement had converted to carbonated hydroxyapatite and remained stable over time. Histological evaluation showed bone apposition on the cement surface without any inflammatory response or fibrous encapsulation. At later time points, all CPCs were completely covered by a thin layer of bone. Osteoclast-like cells present at the interface resorbed parts of the cement mass. Histological and histomorphometrical analyses did not show any significant differences between the three implanted CPCs. The results indicate that the investigated CPC is biocompatible, osteoconductive, as well as osteotransductive and seems to be both biologically safe and effective as a bone void filler.
机译：这项研究的目的是研究一种新开发的磷酸钙水泥（CPC）的理化和生物学特性。将新型水泥与其他两种市售CPC进行了比较。将粉末和液相混合后，将CPC作为糊剂注射到兔股骨远端缺损模型中。在24小时，6周，26周和52周后评估CPC。新颖的CPC易于操作且设置快速。 X射线衍射（XRD）和傅立叶变换红外光谱（FTIR）在不同的注入期表明，水泥已经转变为碳酸羟基磷灰石，并随着时间的推移保持稳定。组织学评估显示骨并置在水泥表面上，没有任何炎症反应或纤维包裹。在稍后的时间点，所有CPC都被一层薄薄的骨头完全覆盖。存在于界面的破骨细胞样细胞吸收了水泥团块的一部分。组织学和组织形态计量学分析未显示三个植入的CPC之间的任何显着差异。结果表明，所研究的CPC具有生物相容性，骨传导性和骨传导性，并且在生物学上安全且有效地用作骨空隙填充剂。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号