Life-Threatening Tumor Lysis Syndrome Within 12 Hours of a Single Dose of Corticosteroid in a Patient with Lymphoma

April Brooks; Grady Wick; Damiano Rondelli; José A. L. Arruda; Kalyani Perumal; Jerrold S. Levine

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Life-Threatening Tumor Lysis Syndrome Within 12 Hours of a Single Dose of Corticosteroid in a Patient with Lymphoma

机译：淋巴瘤患者单次服用皮质类固醇激素后12个小时内威胁生命的肿瘤溶解综合征

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Tumor lysis syndrome is an oncologic emergency characterized by electrolyte derangements and the frequent development of acute renal failure. We describe a patient with acute lymphoblastic lymphoma in whom rapid and severe tumor lysis syndrome developed within 10 h of the administration of a single dose of corticosteroid. Our case and a review of the literature indicate that patients with lymphoproliferative malignancies given a single dose of corticosteroid may be at significant risk for rapid and life-threatening tumor lysis syndrome. We recommend that such patients receive aggressive and frequent laboratory monitoring even in the setting of appropriate prophylaxis.

机译：肿瘤溶解综合征是一种以肿瘤电解质紊乱和急性肾功能衰竭的频繁发生为特征的肿瘤急症。我们描述了患有急性淋巴细胞性淋巴瘤的患者，其中在单剂皮质类固醇给药后10小时内出现了快速而严重的肿瘤溶解综合征。我们的案例和文献综述表明，单剂量给予皮质类固醇激素的淋巴增生性恶性肿瘤患者可能会面临快速且危及生命的肿瘤溶解综合征的重大风险。我们建议即使在采取适当的预防措施的情况下，此类患者也应接受积极主动的频繁实验室检查。

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《Kidney》 |2009年第3期|p.125-128|共4页
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April Brooks; Grady Wick; Damiano Rondelli; José A. L. Arruda; Kalyani Perumal; Jerrold S. Levine;
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1. Management of tumor lysis syndrome with a single fixed dose of rasburicase in Asian lymphoma patients: a case series and literature review. [J] . Chiang J, Chan A, Lian T, Asia-Pacific journal of clinical oncology . 2011,第4期

机译：在亚洲淋巴瘤患者中使用单一固定剂量的rasburicase治疗肿瘤溶解综合征：一个病例系列和文献综述。
2. Management of tumor lysis syndrome with a single fixed dose of rasburicase in Asian lymphoma patients: A case series and literature review [J] . Joen CHIANG, Alexandre CHAN, Tracy LIAN, Asia-Pacific Journal of Clinical Oncology . 2011,第4期

机译：单次固定剂量rasburicase治疗亚洲淋巴瘤患者的肿瘤溶解综合征：病例系列及文献综述
3. A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome [J] . Vadhan-rajS., FayadL.E., FanaleM.A., Annals of oncology: official journal of the European Society for Medical Oncology . 2012,第6期

机译：肿瘤溶解综合征风险患者中单剂量rasburicase与每日五剂的随机试验
4. Predicting lymphoma outcomes and risk factors in patients with primary Sjögren’s Syndrome using gradient boosting tree ensembles [C] . Vasileios C. Pezoulas, Themis P. Exarchos, Athanasios G. Tzioufas, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2019

机译：使用梯度增强树组合预测原发性干燥综合征患者的淋巴瘤结局和危险因素
5. Cardiac arrhythmias in patients with acute coronary syndrome within the first 24 hours of hospitalization. [D] . Winkler, Catherine Evelyn Gerowe. 2009

机译：住院前24小时内患有急性冠脉综合征的患者的心律不齐。
6. A randomized trial of a single-dose rasburicase versus five-daily doses in patients at risk for tumor lysis syndrome [O] . S. Vadhan-Raj, L. E. Fayad, M. A. Fanale, -1

机译：肿瘤溶解综合征风险患者中单剂量rasburicase与每日五剂的随机试验
7. Tumor lysis syndrome provides evidence for dose-intense response for corticosteroids in prolymphocytic leukemia letter [O] . R Jones, JM Pipas, AD Kritz 1993

机译：肿瘤裂解综合征为缓慢性白血病皮质类固醇的剂量激烈响应提供了证据字母

Life-Threatening Tumor Lysis Syndrome Within 12 Hours of a Single Dose of Corticosteroid in a Patient with Lymphoma

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