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Antibacterial activity of zinc oxide-coated nanoporous alumina

机译:氧化锌包覆的纳米多孔氧化铝的抗菌活性

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摘要

Nanoporous alumina membranes, also known as anodized aluminum oxide membranes, are being investigated for use in treatment of burn injuries and other skin wounds. In this study, atomic layer deposition was used for coating the surfaces of nanoporous alumina membranes with zinc oxide. Agar diffusion assays were used to show activity of zinc oxide-coated nanoporous alumina membranes against several bacteria found on the skin surface, including Bacillus subtilis, Escherichia coli, Staphylococcus aureus, and Staphylococcus epidermidis. On the other hand, zinc oxide-coated nanoporous alumina membranes did not show activity against Pseudomonas aeruginosa, Enterococcus faecalis, and Candida albicans. These results suggest that zinc oxide-coated nanoporous alumina membranes have activity against some Gram-positive and Gram-negative bacteria that are associated with skin colonization and skin infection.
机译:纳米多孔氧化铝膜,也称为阳极氧化铝膜,正在研究中,用于治疗烧伤和其他皮肤伤口。在这项研究中,原子层沉积用于用氧化锌涂覆纳米多孔氧化铝膜的表面。琼脂扩散试验用于显示氧化锌涂层的纳米多孔氧化铝膜对皮肤表面上发现的几种细菌的活性,这些细菌包括枯草芽孢杆菌,大肠杆菌,金黄色葡萄球菌和表皮葡萄球菌。另一方面,氧化锌涂层的纳米多孔氧化铝膜没有表现出对铜绿假单胞菌,粪肠球菌和白色念珠菌的活性。这些结果表明,涂​​覆氧化锌的纳米多孔氧化铝膜对某些与皮肤定植和皮肤感染有关的革兰氏阳性和革兰氏阴性细菌具有活性。

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  • 来源
    《Materials Science and Engineering》 |2012年第12期|p.992-998|共7页
  • 作者单位

    Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Box 7115, Raleigh, NC 27695-7115, USA;

    Department of Materials Science and Engineering, North Carolina State University, Box 7907, Raleigh, NC 27695-7907, USA;

    Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Box 7115, Raleigh, NC 27695-7115, USA,Division of Biology, Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, Silver Spring, MD 20993. USA;

    Center for Nanoscale Science and Engineering, North Dakota State University, 1805 Research Park Drive, Fargo, ND 58102, USA;

    Center for Nanoscale Science and Engineering, North Dakota State University, 1805 Research Park Drive, Fargo, ND 58102, USA;

    Center for Nanoscale Science and Engineering, North Dakota State University, 1805 Research Park Drive, Fargo, ND 58102, USA;

    Energy Systems Division, Argonne National Laboratory, Argonne, IL 60439, USA;

    Energy Systems Division, Argonne National Laboratory, Argonne, IL 60439, USA;

    Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Box 7115, Raleigh, NC 27695-7115, USA,Department of Materials Science and Engineering, North Carolina State University, Box 7907, Raleigh, NC 27695-7907, USA,Joint Department of Biomedical Engineering, Univer-sity of North Carolina and North Carolina State University, Raleigh, NC 27695-7115,USA;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    aluminum oxide; zinc oxide; atomic layer deposition; nanoporous material; antibacterial material;

    机译:氧化铝氧化锌原子层沉积;纳米多孔材料;抗菌材料;

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