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首页> 外文期刊>Materials science & engineering >Effect of composition on in vitro degradability of Ti-Mg metal-metal composites
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Effect of composition on in vitro degradability of Ti-Mg metal-metal composites

机译：组成对Ti-Mg金属-金属复合材料体外降解性能的影响

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摘要

In this work, Ti and Mg alloys were made into composites by using spark plasma sintering, in order to combine the high stiffness of Ti and biodegradability of Mg alloys. The effect of the content of Mg-3Zn alloy on the degradability was studied by using electrochemical corrosion, immersion in simulated body fluid and incubation of Saos-2 cells. The results show that Ti-Mg metal-metal composites (MMCs) exhibit low Young's modulus (31-48 GPa) and good yield strength (616.5-642.8 MPa). The modulus and strength both decrease with the content of Mg-3Zn alloy increasing. The electrochemical corrosion rates of Ti-Mg MMCs were much lower than that of monolithic Mg-3Zn alloys. After an immersion for 21 days, Ti matrix remained integrity and Mg phase dissolved in the solution, inducing the formation of apatite layer on the MMCs. The precipitation of apatite increased with the content of Mg-3Zn alloy increasing. In vitro study indicated that Ti-10Mg and Ti-20 Mg MMCs possessed good biocompatibility to Saos-2 cells, while the biocompatibility of Ti-30 Mg MMCs decreased slightly. In summary, Ti-Mg MMCs are promising implant materials with adjustable degradation rates and improved biocompatibility for orthopedic applications.
机译：在这项工作中，通过火花等离子体烧结将Ti和Mg合金制成复合材料，以兼具Ti的高刚度和Mg合金的可生物降解性。通过电化学腐蚀，浸入模拟体液和孵育Saos-2细胞，研究了Mg-3Zn合金含量对可降解性的影响。结果表明，Ti-Mg金属-金属复合材料（MMCs）表现出较低的杨氏模量（31-48 GPa）和良好的屈服强度（616.5-642.8 MPa）。随着Mg-3Zn合金含量的增加，模量和强度均降低。 Ti-Mg MMC的电化学腐蚀速率远低于整体Mg-3Zn合金。浸入21天后，Ti基体保持完整性，并且Mg相溶解在溶液中，从而在MMC上形成了磷灰石层。随着Mg-3Zn合金含量的增加，磷灰石的析出量增加。体外研究表明，Ti-10Mg和Ti-20 Mg MMC与Saos-2细胞具有良好的生物相容性，而Ti-30 Mg MMC的生物相容性略有下降。总之，Ti-Mg MMC是有前途的植入物材料，具有可调节的降解速率和改善的骨相容性生物相容性。

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