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首页> 外文期刊>Materials science & engineering >Maxillary sinus floor augmentation on humans: Packing simulations and 8 months histomorphometric comparative study of anorganic bone matrix and β-tricalcium phosphate particles as grafting materials
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Maxillary sinus floor augmentation on humans: Packing simulations and 8 months histomorphometric comparative study of anorganic bone matrix and β-tricalcium phosphate particles as grafting materials

机译：人体上颌窦底增强术：无机骨基质和β-磷酸三钙颗粒作为移植材料的包装模拟和8个月组织形态学比较研究

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摘要

The present study compares the behaviour of an anorganic bone matrix material and a synthetic β-Tricalcium phosphate employed as grafting materials in a sinus floor augmentation two step protocol in humans. In order to estimate the initial occupation level for the two materials, an 'in vitro' simulation has been performed to analyse macroporosity created due to particle packing in terms of porosity and interparticle distances. Grafting in the sinus floor augmentation was performed by filling the defects only with pure grafting materials without autogenous bone addition. The new-bone generated is 100% based on the osteoconductive properties of the grafted materials in contact with physiological fluids. The implants were placed 8 months after the grafting procedure. All the implanted positions were biopsied and embedded in methacrylate resin. Histomorphometric analyses were done over thin film undecalcified sections. Packing simulations allow establishing a comparison of the resorbed volumes related to the initial occupancy of the grafting materials inside the defect. The nature of this interconnected pore network is very alike for either material so new-bone generated was similar (～35 vol.%).
机译：本研究比较了人工骨基质材料和人工合成的β-磷酸三钙磷酸酯在人鼻窦底隆突两步方案中用作移植材料的行为。为了估计两种材料的初始职业水平，已进行了“体外”模拟，以分析由于孔隙和孔隙间距离造成的颗粒堆积而产生的大孔隙。通过仅用纯移植材料填充缺损而无自体骨添加的方式来进行窦底隆起的移植。基于与生理流体接触的接枝材料的骨传导特性，产生的新骨为100％。移植后8个月放置植入物。对所有植入位置进行活检并包埋在甲基丙烯酸酯树脂中。对薄膜未脱钙的切片进行了组织形态分析。堆积模拟可以建立与缺陷内部接枝材料初始占有率相关的吸收量的比较。每种材料的相互连接的孔隙网络的性质非常相似，因此产生的新骨相似（〜35 vol。％）。

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  • 来源
    《Materials science & engineering》 |2010年第5期|p.763-769|共7页
  • 作者

    A. Martinez; J. Franco; E. Saiz; F. Guitian;

  • 作者单位

    Facultad de Medicina y Odontologia, University of Santiago de Compostela, Rua San Francisco s 15782 Santiago de Compostela, Spain;

    Lawrence Berkeley National Laboratory, 1 Cyclotron Rd Mail stop 62R0203 Berkeley, CA 94720, USA;

    Lawrence Berkeley National Laboratory, 1 Cyclotron Rd Mail stop 62R0203 Berkeley, CA 94720, USA UK Centre for Advanced Structural Ceramics, Department of Materials, Imperial College, London;

    Instituto de Ceramica de Galicia, Av Mestre Mateo s, 15782 Santiago de Compostela, Spain;

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  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    grafting particulates; calcium phosphates; histomorphometry; packing simulations; sinus floor augmentation;

    机译：接枝颗粒;磷酸钙;组织形态计量学包装模拟;窦底增大;

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