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Transperitoneal administration of dissolved hydrogen for peritoneal dialysis patients: a novel approach to suppress oxidative stress in the peritoneal cavity

机译:经腹膜溶解氢用于腹膜透析患者:一种抑制腹膜腔氧化应激的新方法

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摘要

Background Oxidative stress (OS) related to glucose degradation products such as methylglyoxal is reportedly associated with peritoneal deterioration in patients treated with peritoneal dialysis (PD). However, the use of general antioxidant agents is limited due to their harmful effects. This study aimed to clarify the influence of the novel antioxidant molecular hydrogen (H2) on peritoneal OS using albumin redox state as a marker.
机译:背景技术据报道,在接受腹膜透析(PD)治疗的患者中,与葡萄糖降解产物(如甲基乙二醛)相关的氧化应激(OS)与腹膜恶化有关。但是,由于它们的有害作用,一般抗氧化剂的使用受到限制。本研究旨在以白蛋白氧化还原态为标志物,阐明新型抗氧化剂分子氢(H2)对腹膜OS的影响。

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