Metabolic footprint of Lactobacillus acidophilus NCFM at different pH

Karolina Sulek; Henrik Lauritz Frandsen; Jørn Smedsgaard; Thomas Hjort Skov; Andrea Wilcks; Tine Rask Licht

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Metabolic footprint of Lactobacillus acidophilus NCFM at different pH

机译：不同pH下嗜酸乳杆菌NCFM的代谢足迹

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Lactobacillus acidophilus NCFM is a well known microorganism from the genomic and probiotic point of view. In order to analyze the potential interactions of NCFM with the surrounding environment, in vitro tests with the metabolic footprinting approach were performed. It was found that NCFM increased the concentration of lactic acid, succinic acid, adenine and arginine in the medium. The metabolism of NCFM did not change significantly between pH 5 and 7, suggesting that other environmental factors than pH might have bigger impact on its colonization throughout the gastrointestinal tract.

机译：从基因组和益生菌的角度来看，嗜酸乳杆菌NCFM是一种众所周知的微生物。为了分析NCFM与周围环境的潜在相互作用，使用代谢足迹法进行了体外测试。发现NCFM增加了培养基中乳酸，琥珀酸，腺嘌呤和精氨酸的浓度。在pH 5至7之间，NCFM的代谢没有明显变化，这表明pH以外的其他环境因素可能对其在整个胃肠道中的定殖产生更大的影响。

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《Metabolomics》 |2012年第2期|p.244-252|共9页
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Karolina Sulek; Henrik Lauritz Frandsen; Jørn Smedsgaard; Thomas Hjort Skov; Andrea Wilcks; Tine Rask Licht;
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1. The effect of probiotics (Lactobacillus rhamnosus HN001, Lactobacillus paracasei LPC-37, and Lactobacillus acidophilus NCFM) on the availability of minerals from Dutch-type cheese [J] . Marek Aljewicz, Ewa Siemianowska, Grazyna Cichosz, Journal of dairy science . 2014,第8期

机译：益生菌（鼠李糖乳杆菌HN001，副干酪乳杆菌LPC-37和嗜酸乳杆菌NCFM）对荷兰奶酪中矿物质供应的影响
2. Erratum: Hunaefi, D., et al. The Effect of Lactobacillus plantarum ATCC 8014 and Lactobacillus acidophilus NCFM Fermentation on Antioxidant Properties of Selected in Vitro Sprout Culture of Orthosiphon aristatus (Java Tea) as a Model Study. Antioxidants 2012, 1, 4–32 [J] . Antioxidants . 2015,第4期

机译：勘误表：Hunaefi，D.等。作为模型研究，植物乳杆菌ATCC 8014和嗜酸乳杆菌NCFM发酵对选定的Orthosiphon aristatus（Java茶）体外新芽培养物抗氧化特性的影响。抗氧化剂2012，1，4–32
3. The Effect of Lactobacillus plantarum ATCC 8014 and Lactobacillus acidophilus NCFM Fermentation on Antioxidant Properties of Selected in Vitro Sprout Culture of Orthosiphon aristatus (Java Tea) as a Model Study [J] . Dase Hunaefi, Divine N. Akumo, Heidi Riedel, Antioxidants . 2012,第1期

机译：模型研究植物乳杆菌ATCC 8014和嗜酸乳杆菌NCFM发酵对精选拟南芥（Java Tea）体外萌芽培养物抗氧化特性的影响
4. Towards the Reconstruction of the Genome-Scale Metabolic Model of Lactobacillus acidophilus La-14 [C] . Emanuel Cunha, Ahmad Zeidan, Oscar Dias International Conference on Practical Applications of Computational Biology Bioinformatics . 2021

机译：朝向乳杆菌基因组尺度代谢模型的重建研究
5. Functional analysis of adhesion factors and signaling mechanisms in Lactobacillus acidophilus NCFM. [D] . Buck, B. Logan. 2006

机译：嗜酸乳杆菌NCFM中粘附因子和信号传导机制的功能分析。
6. Erratum: Hunaefi D. et al. The Effect of Lactobacillus plantarum ATCC 8014 and Lactobacillus acidophilus NCFM Fermentation on Antioxidant Properties of Selected in Vitro Sprout Culture of Orthosiphon aristatus (Java Tea) as a Model Study. Antioxidants 2012 1 4–32 [O] . 2015

机译：勘误表：HunaefiD.等。作为模型研究植物乳杆菌ATCC 8014和嗜酸乳杆菌NCFM发酵对选定的Orthosiphon aristatus（Java茶）体外新芽培养物抗氧化特性的影响。抗氧化剂201214–32
7. The effect of different in vitro conditions on the metabolic footprint of Lactobacillus acidophilus NCFM [O] . Sulek Karolina, Wilcks Andrea, Licht Tine Rask, 2010

机译：不同体外条件对嗜酸乳杆菌NCFm代谢足迹的影响
8. THE USE OF PHOSPHORUS-32 TO EVALUATE PHOSPHORUS REQUIREMENTS OF LACTOBACILLUS ACIDOPHILUS [R] . NORMAN O. HARRIS 1957

机译：使用磷-32评估乳酸杆菌的磷需求

Metabolic footprint of Lactobacillus acidophilus NCFM at different pH

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