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Separation by nanoparticles plasmonic resonance with low stress in microfluidics channel (analytical and design)

机译:在微流体通道中通过低应力的纳米粒子等离子体共振分离(分析和设计)

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摘要

In this study, nanoparticles near-field plasmonic resonance is used to improve the traditional cell separation main outputs such as viability and efficiency. The live cells viability is severely depend on stresses, which are applied on cells in the microfluidics channel. Hence, for improving the cell viability, the enforced stresses inside of the structure should be declined. The major factors of the enforced stresses are related to the electric field non-uniformity, which are attributed to the hurdles and applied voltage magnitude. Therefore, in this study, a new structure is presented and thereby, the magnitude of the applied stresses on live cells is minimised which is contributed to the decreasing the non-uniformity strength of channel. It should be noted that in the new structure two arrays of nanoparticles were used to produce a short range and localised non-uniform electrical field because of their near-field plasmonic resonance. Hence, the enforced stress on the live cell severely decreased at the far-field and confined at the small section of the channel. It is due to, the near-field plasmonic amplitude is dramatically disappeared by increasing distance, hence, the cells far from the nanoparticles will be endured the low level but effective amount of the optical force.
机译:在这项研究中,纳米粒子近场等离子体共振用于改善传统细胞分离的主要输出,如生存能力和效率。活细胞的生存能力严重依赖于应力,应力作用在微流体通道中的细胞上。因此,为了提高细胞活力,应该降低结构内部的强制应力。施加应力的主要因素与电场不均匀有关,电场不均匀归因于障碍和施加的电压幅度。因此,在这项研究中,提出了一种新的结构,从而使对活细胞施加的应力的大小最小化,这有助于减小通道的不均匀强度。应当指出的是,在新结构中,由于它们的近场等离子体共振,所以使用了两个纳米颗粒阵列来产生短距离和局部的不均匀电场。因此,在活细胞上施加的压力在远场严重降低,并局限于通道的小部分。这是由于,随着距离的增加,近场等离激元振幅急剧消失,因此,远离纳米颗粒的细胞将承受低水平但有效量的光学力。

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