NIH to balance sex in cell and animal studies

Janine A. Clayton; Francis S. Collins

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NIH to balance sex in cell and animal studies

机译：NIH在细胞和动物研究中平衡性别

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More than two decades ago, the US National Institutes of Health (NIH) established the Office of Research on Women's Health (ORWH). At that time, the Congressional Caucus for Women's Issues, women's health advocacy groups and NIH scientists and leaders agreed that excluding women from clinical research was bad for women and bad for science. In 1993, the NIH Revitalization Act required the inclusion of women in NIH-funded clinical research. Today, just over half of NIH-funded clinical-research participants are women. We know much more about the role of sex and gender in medicine, such as that low-dose aspirin has different preventive effects in women and men, and that drugs such as Zolpidem, used to treat insomnia, require different dosing in women and men.

机译：二十多年前，美国国立卫生研究院（NIH）成立了妇女健康研究办公室（ORWH）。当时，国会妇女问题核心小组，妇女健康倡导团体以及美国国立卫生研究院的科学家和领导人一致认为，将妇女排除在临床研究之外对妇女不利，对科学不利。 1993年，《 NIH振兴法》要求将女性纳入NIH资助的临床研究中。如今，美国国立卫生研究院资助的临床研究参与者中，一半以上是女性。我们对性别在医学中的作用了解更多，例如，低剂量阿司匹林对男女的预防作用不同，用于治疗失眠的药物如唑吡坦（Zolpidem）对男女的剂量要求也不同。

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来源
《Nature》 |2014年第7500期|282-283|共2页
作者
Janine A. Clayton; Francis S. Collins;
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作者单位

US National Institutes of Health Office of Research on Women's Health;

US National Institutes of Health, Bethesda, Maryland, USA;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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NIH to balance sex in cell and animal studies

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