Bilateral tendency in Hydra

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Bilateral tendency in Hydra

机译：九头蛇的双边趋势

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Bilaterian animals have three body axes-anterior-posterior, dorso-ventral and left-right-each associated with a key signalling factor in development: Wnt, Bmp and Nodal, respectively. Cnidarians, which include jellyfish, sea anemones and hydra, are a sister group to bilaterians. They are simpler, and appear to be cylindrical and radially symmetrical. This paper describes a gene related to Nodal in Hydra. Expressed exclusively in developing lateral buds, the Nodal-related (Ndr) gene is vital for setting up a new body axis, distinct from that of the parent, in the developing bud. Ndr acts within a pathway resembling the Nodal/Pitx/β-catenin signalling cassette found in vertebrates, a regulatory system likely to have existed before the divergence of cnidarians and bilaterians.

机译：双语动物具有三个身体轴，分别是前-后，背-腹和左右，分别与发育中的关键信号因子相关：Wnt，Bmp和Nodal。包括水母，海葵和九头蛇在内的颅骨科动物是双语生物的姊妹群体。它们更简单，并且看起来是圆柱形的并且径向对称。本文描述了与九头蛇中Nodal相关的基因。节点相关（Ndr）基因仅在发育中的侧芽中表达，对于在发育中的芽中建立不同于亲本的新体轴至关重要。 Ndr在类似于脊椎动物中发现的Nodal / Pitx /β-catenin信号传导盒的途径中起作用，这是一个在虫和双翅类动物分化之前就已经存在的调节系统。

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《Nature》 |2014年第7515期|373-373|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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Bilateral tendency in Hydra

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