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Retraction: Branched tricarboxylic acid metabolism in Plasmodium falciparum

机译:缩回:恶性疟原虫中的支链三羧酸代谢

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We retract this Letter, which reported both reductive and oxidative tricarboxylic acid (TCA) metabolism in Plasmodium falciparum parasites ('branched TCA metabolism').The data for metabolic labelling of TCA intermediates remain reliable, but we have come to realize that the interpretation presented is incorrect. Although there is both reductive and oxidative TCA cycle flux in P.falciparum-iniected red blood cell (RBC) cultures (as we reported), new data from the Llinas and Vaidya groups (manuscript in preparation) suggests that the reductive flux occurs primarily in the RBCs and not in the parasite itself.
机译:我们撤回了这封信,该信报道了恶性疟原虫寄生虫中的还原性和氧化性三羧酸(TCA)代谢(``分支的TCA代谢'').TCA中间体代谢标记的数据仍然可靠,但我们已经意识到,提出的解释是不正确的。尽管在恶性疟原虫感染的红细胞(RBC)培养物中同时存在还原性和氧化性TCA循环通量(如我们所报道),但来自Llinas和Vaidya组(制备中的手稿)的新数据表明,还原性通量主要发生在红细胞而不是寄生虫本身。

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