Immunity let loose

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Immunity let loose

机译：免疫力放松

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Experimental therapies that unleash the immune system to fight cancer, by blocking 'checkpoint inhibitors', continue to show promise in early clinical trials. Immune checkpoint inhibitors prevent autoimmunity, and can rein in the immune response against tumours. Antoni Ribas at the University of California, Los Angeles, and his colleagues tested lambrolizumab, a compound that blocks a checkpoint inhibitor called PD-1, in 135 people with advanced melanoma. Tumours shrank by at least 30% in 38% of the patients.

机译：通过阻断“检查点抑制剂”释放出免疫系统来对抗癌症的实验疗法在早期临床试验中继续显示出希望。免疫检查点抑制剂可防止自身免疫，并可以控制针对肿瘤的免疫反应。加利福尼亚大学洛杉矶分校的安东尼·里巴斯（Antoni Ribas）和他的同事在135名晚期黑色素瘤患者中测试了lambrolizumab，该化合物可阻断称为PD-1的检查点抑制剂。 38％的患者的肿瘤缩小了至少30％。

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《Nature》 |2013年第7453期|140-141|共2页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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机译：会议-1928年6月13日：腹膜松动的尸体：注意到在道格拉斯的小袋中发现了一个松散的卵巢（？）的情况

Immunity let loose

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