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Mind how you go

机译:小心你怎么走

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When Nature broke the news in December 2011 that Novartis was to close its brain research facility in Basel, Switzerland, the story noted that this move closely followed similar cuts by rival pharmaceutical firms. As a report from the European College of Neuropsychopharmacology had warned a few months earlier, the abandonment of research into new psychiatric drugs by AstraZeneca, GlaxoSmithKline and others meant that "withdrawal of research resources is a withdrawal of hope for patients and their families" That 2011 story did offer a glimmer of optimism. Novartis, we reported, was not deserting these patients and families completely. It planned to switch focus - away from conventional neuroscience-drug development based on chemistry and small molecules, and towards treatments based on the genetics of psychiatric and cognitive disorders. As we report this week on page 153, the company has made good on its promise. It has reopened its neuroscience division, now at its global drug-discovery headquarters in Cambridge, Massachusetts, and has hired Ricardo Dolmetsch, a former senior director at the Allen Institute for Brain Science in Seattle, Washington, to head it.
机译:当《自然》杂志在2011年12月爆料诺华即将关闭其在瑞士巴塞尔的大脑研究设施的消息时,这个故事指出,此举紧随竞争对手制药公司的类似削减。正如欧洲神经心理药理学院的一份报告在几个月前警告说的那样,阿斯利康,葛兰素史克等人放弃了对新型精神药物的研究,这意味着“撤回研究资源对患者及其家庭带来了希望”。故事确实带来了一丝乐观。据我们报道,诺华并没有完全抛弃这些患者和家人。它计划将重点从传统的基于化学和小分子的神经科学药物开发转向基于精神和认知障碍遗传学的治疗。正如我们本周在第153页报道的那样,该公司已兑现了诺言。它已经重新开放了其神经科学部门,该部门现在位于马萨诸塞州剑桥的全球药物发现总部,并聘请了华盛顿西雅图艾伦脑科学研究所的前高级主管里卡多·多尔梅特奇(Ricardo Dolmetsch)担任该小组的负责人。

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    《Nature》 |2013年第7470期|141-141|共1页
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  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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