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Cells grow in sleeping brains

机译:细胞在睡眠的大脑中生长

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Sleep seems to wake up a type of brain cell that maintains healthy neuron signalling. Chiara Cirelli and her colleagues at the University of Wisconsin-Madison analysed support cells called oligodendrocytes that wrap around neurons and protect them with a specialized sheath that helps their signals to travel faster.They collected oligodendrocytes and their precursor cells from mice after the animals had experienced a few hours of sleep or wakefulness and then profiled the expression of newly transcribed genes. Genes that were most active during wakefulness were involved in cell differentiation and death. By contrast, genes that were expressed during sleep promoted cell growth and the production of protective sheaths.
机译:睡眠似乎可以唤醒一种维持健康神经元信号的脑细胞。威斯康星大学麦迪逊分校的Chiara Cirelli和她的同事分析了称为少突胶质细胞的支持细胞,这些细胞包裹在神经元周围并用专门的鞘来保护它们,以帮助它们的信号更快地传播。几个小时的睡眠或清醒,然后分析新转录的基因的表达。在清醒过程中最活跃的基因参与细胞分化和死亡。相反,睡眠期间表达的基因促进细胞生长和保护鞘的产生。

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  • 来源
    《Nature》 |2013年第7474期|9-9|共1页
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  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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