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What to do and how

机译:怎么做以及如何

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Neurons typically receive inputs from many thousands of others. This dense connectivity suggests that brain functions such as perception, cognition and motor control result from the concerted activity of populations of neurons, rather than from single-cell activity. Nevertheless, neuroscientists have long made discoveries by recording from, and thinking about, one neuron at a time. But more-recent developments in electrophysiological recording and imaging of the dynamics of hundreds of neurons simultaneously, alongside advances in data-analytic and theoretical tools, highlight the importance of understanding the relationship between the dynamics of large neural populations and the computations those dynamics embody. In a tour de force reported on page 78 of this issue, Mante et al. use electrophysiology together with sophisticated behavioural and neural modelling to add a population-dynamics view of the computations underlying flexible, context-dependent behaviour.
机译:神经元通常从成千上万的其他人接收输入。这种紧密的联系表明,诸如感知,认知和运动控制之类的大脑功能是由神经元群体协调一致的活动而不是单细胞活动引起的。然而,神经科学家长期以来通过一次记录和思考一个神经元来做出发现。但是,同时进行数百种神经元动力学的电生理记录和成像的最新进展,以及数据分析和理论工具的进步,突出了理解大型神经种群动力学与这些动力学所体现的计算之间的关系的重要性。在本期第78页报道的环法自行车赛中,Mante等人。将电生理学与复杂的行为和神经模型一起使用,可以为基于灵活,与上下文相关的行为的计算添加总体动力学视图。

著录项

  • 来源
    《Nature》 |2013年第7474期|45-47|共3页
  • 作者单位

    Princeton Neuroscience Institute and Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA;

    Princeton Neuroscience Institute and Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA,Howard Hughes Medical Institute;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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