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Proteins help solve taxonomy riddle

机译:蛋白质有助于解决分类难题

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摘要

A 300-year-old pickled fetus that was classified by Carl Linnaeus as the type specimen of the Asian elephant has been proved to be an African elephant - by the use of the emerging technology of ancient proteomics.Evolutionary geneticist Tom Gilbert, whose University of Copenhagen lab owns one of the worlds most advanced DNA sequencing machines, had failed to identify the species from a DNA sample seven years ago because it was too degraded. To sidestep this problem, he and his colleague Enrico Cappellini decided to run an advanced protein analysis using a sample from the oesophagus of the fetus, held in the National Museum of Natural History in Stockholm. "Clearly it's got protein, because the damn thing still exists," Gilbert says. The team sequenced several proteins in the specimen that were known to vary between elephant species, and each pointed to an African origin for the fetus. Linnaeus assigned the elephant fetus as the type specimen of the Asian elephant (Elephas maximus), but zoologists had long suspected that it was in fact an African elephant (now called Loxodonta africana).
机译:进化遗传学家汤姆·吉尔伯特(Tom Gilbert)是进化遗传学家汤姆·吉尔伯特(Tom Gilbert),他被卡尔·林奈(Carl Linnaeus)归类为亚洲象的典型标本,具有300年的历史,被证明是非洲象。哥本哈根实验室拥有世界上最先进的DNA测序仪之一,七年前由于其降解太快而未能从DNA样品中鉴定出该物种。为了避免这个问题,他和他的同事恩里科·卡佩里尼(Enrico Cappellini)决定使用来自斯德哥尔摩国家自然历史博物馆的胎儿食道样品进行高级蛋白质分析。吉尔伯特说:“显然它含有蛋白质,因为该死的东西仍然存在。”研究小组对样本中的几种蛋白质进行了测序,这些蛋白质已知在大象种类之间会有所不同,每种都指向胎儿的非洲血统。林奈(Linnaeus)将大象胎儿指定为亚洲大象(Elephas maximus)的典型标本,但动物学家早就怀疑它实际上是一头非洲大象(现在称为非洲象)。

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  • 来源
    《Nature》 |2013年第7474期|18-19|共2页
  • 作者

    EWEN CALLAWAY;

  • 作者单位
  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
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