The wrap that feeds neurons

JOHANNE E.RINHOLM; LINDA H. BERCERSEN

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The wrap that feeds neurons

机译：包裹神经元的食物

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The white matter of the central nervous system consists of nerve fibres (axons) wrapped in insulating myelin — a membranous, lipid-rich sheath that is laid down by cells known as oligodendrocytes. In the peripheral nervous system, fast-conducting nerve fibres are similarly wrapped in myelin by Schwann cells. The sheath allows nerve impulses to move at a much higher speed than in non-myelinated axons, and supports neurons in other, less-well-understood ways~1. On page 443 of this issue, Lee et al.~2 describe how the myelin wrap provides lactate, an energy-generating metabolite, to axons.

机译：中枢神经系统的白质由包裹在绝缘髓鞘中的神经纤维（轴突）组成，髓鞘是一种膜状，富含脂质的鞘，被称为少突胶质细胞的细胞所覆盖。在周围神经系统中，快速传导的神经纤维被雪旺氏细胞包裹在髓鞘中。鞘层使神经冲动的移动速度比无髓鞘的轴突快得多，并以其他不太容易理解的方式支持神经元〜1。 Lee等[2]在第443页上描述了髓磷脂包裹物如何为轴突提供乳酸（一种能产生能量的代谢产物）。

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来源
《Nature》 |2012年第7408期|p.435-436|共2页
作者
JOHANNE E.RINHOLM; LINDA H. BERCERSEN;
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作者单位

Janelia Farm Research Campus, Howard Hughes Medical Institute,Ashburn, Virginia 20147, USA,Centre for Molecular Biology and Neuroscience, and the Department of Anatomy, Institute of Basic Medical Sciences,University of Oslo, Oslo N-0317, Norway;

Center for Healthy Aging, Department of Neuroscience and Pharmacology, University of Copenhagen, 2200 Copenhagen N, Denmark,Centre for Molecular Biology and Neuroscience, and the Department of Anatomy, Institute of Basic Medical Sciences,University of Oslo, Oslo N-0317, Norway;

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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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机译：WRAP53对于Cajal体形成和将运动神经元复合体的存活靶向Cajal体至关重要

The wrap that feeds neurons

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