Actors in the cell reprogramming drama

KYLE M. LOH; BING LIM

首页> 外文期刊>Nature >Actors in the cell reprogramming drama

【24h】

Actors in the cell reprogramming drama

机译：细胞重编剧中的演员

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Coercing cells into adopting new fates for example, turning skin into muscle, brain or heart-is one of the most impressive achievements of modern biology. Prominent among these feats is the transformation of skin cells into induced pluripotent stem cells (iPSCs)4. In contrast to skin cells (fibroblasts) and other differentiated cells, which cannot generate any other cell type except their own, iPSCs have the remarkable ability to give rise to any kind of cell in the body4. Yet the molecular changes that drive this cellular metamorphosis have remained a mystery. For the first time, Doege et al.(page 652) provide a mechanistic explanation for how the earliest phases of such a dramatic change in cell fate might be executed.

机译：强迫细胞采取新的命运，例如将皮肤变成肌肉，大脑或心脏，是现代生物学最令人印象深刻的成就之一。这些专长中最突出的是皮肤细胞向诱导多能干细胞（iPSC）的转化4。与皮肤细胞（成纤维细胞）和其他分化的细胞（除了自身不能产生其他任何细胞类型）相反，iPSC具有在体内产生任何类型细胞的卓越能力4。然而，驱动这种细胞变态的分子变化仍然是一个谜。 Doege等人（第652页）首次提供了一种机制性的解释，说明细胞命运的这种戏剧性变化的最早阶段是如何执行的。

著录项

来源
《Nature》 |2012年第7413期|p.599-600|共2页
作者
KYLE M. LOH; BING LIM;
展开▼
作者单位

Department of Developmental Biology,Stanford University School of Medicine,Stanford,California 94305,USA;

Stem Cell & Developmental Biology Group,Genome Institute of Singapore,138672 Singapore,and at the Beth Israel Deaconess Medical Center,Boston,Massachusetts;

展开▼
收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词

相似文献

外文文献
中文文献
专利

1. Actors loving the drama [J] . Lewis Goody, Kae Alexander Canal boat and inland waterways . 2018,第apra期

机译：热爱戏剧的演员
2. An unknown factor born by breaking conventional relationships between actors and audience. A totally unique atmosphere. That tension of chaotic moment adds quality to drama [J] . Hanae Komachi AXIS: Concepts on the Horizon . 2016,第180期

机译：打破演员和观众之间的传统关系而产生的未知因素。完全独特的气氛。混乱时刻的紧张感为戏剧增添了品质
3. Editorial: Dysmetabolism, Obesity, and Inflammation: Three Prominent Actors in the Drama of Major Neuropsychiatric Disorders [J] . Tommaso Cassano, Luca Steardo Frontiers in Neuroscience . 2016,第1期

机译：社论：代谢不良，肥胖和炎症：主要神经精神疾病戏剧中的三个著名演员
4. Differential adhesion strength as a molecular signature for rapid separation of partially reprogrammed cells from human stem cell reprogramming cultures [C] . Ankur Singh, Shalu Suri, Jamie M Chilton, Society for Biomaterials annual meeting and exposition . 2014

机译：差异粘附强度作为从人干细胞重编程培养物中快速分离部分重编程细胞的分子特征
5. Translating for actors: Strategies derived from incorporating the actor's approach to text into the art and craft of drama translation (Jean Cocteau). [D] . Baity, Linda Sullivan. 2001

机译：演员翻译：将演员的文字处理方法纳入戏剧翻译的艺术和手法中而得出的策略（让·科克托）。
6. ELTD1—An Emerging Silent Actor in Cancer Drama Play [O] . Ani-Simona Sevastre, Iuliana M. Buzatu, Carina Baloi, 2021

机译：ELTD1-癌症戏剧戏剧中的一个新兴的沉默演员
7. Giving Voice to the Hero Within:The Combination of Two Methodologies for Training the Actor/Performer-- The Use of Ritual Poetic Drama Within the African Continuum andArchetypes for the Actor/SingerAs Explored in the Performances of A Thousand Faces: Every Day HeroesA Deconstruction of The Hero With A Thousand Faces by Joseph Campbell [O] . Enrico-Johnson Olisa-Mequella F. 2010

机译：向内心的英雄发出声音：两种培训演员/表演者的方法的组合-仪式诗戏剧在非洲连续体中的运用和演员/歌手的原型正如在《千张面孔》的表演中探讨的：“每天的英雄”约瑟夫·坎贝尔解构的《千面英雄》

Actors in the cell reprogramming drama

摘要

著录项

相似文献

相关主题

期刊订阅