N-myristoyltransferase inhibitors as new leads to treat sleeping sickness

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• 来源
  《Nature》 |2010年第7289期|728-732|共5页
• 作者

  Julie A. Frearson; Stephen Brand; Stuart P. McElroy; Laura A. T. Cleghorn; Ondrej Smid; Laste Stojanovski; Helen P. Price; M. Lucia S. Guther; Leah S. Torrie; David A. Robinson; Irene Hallyburton; Chidochangu P. Mpamhanga; James A. Brannigan; Anthony J. Wilkinson; Michael Hodgkinson; Raymond Hui; Wei Qiu; Olawale G. Raimi; Daan M. F. van Aalten; Ruth Brenk; Ian H. Gilbert; Kevin D. Read; Alan H. Fairlamb; Michael A. J. Ferguson; Deborah F. Smith; Paul G. Wyatt;

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• 作者单位

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, Heslington, York YO10 5YW, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK;

  Structural Biology Laboratory, Department of Chemistry, University of York, Heslington, York YO10 5YW, UK;

  Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, Heslington, York YO10 5YW, UK;

  Structural Genomics Consortium, University of Toronto, MaRS South Tower, 7th Floor, 101 College Street, Toronto, Ontario M5G 1L7, Canada;

  Structural Genomics Consortium, University of Toronto, MaRS South Tower, 7th Floor, 101 College Street, Toronto, Ontario M5G 1L7, Canada;

  Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK;

  Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

  Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, Heslington, York YO10 5YW, UK;

  Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, University of Dundee, Dundee DD1 5EH, UK;

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