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The whole nine months

机译:整个九个月

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摘要

The human uterus is not a tranquil nursery. At least one in 30 babies who make it through have health problems caused by genetic mutations and chromosomal misbehaviour. The fetus is also vulnerable to damaging external pressures that are less well understood. In Origins, journalist Annie Murphy Paul reviews the evidence that pre-birth experiences affect our health later in life. Paul recounts the mid-twentieth-century scandals, involving two drugs given to pregnant women, that made the bio-medical community aware that fetuses could be sensitive to medications that are harmless to adults. Thalidomide, which was prescribed for morning sickness and approved for clinical use before it was common to rigorously test drugs for all eventualities, caused abnormal limb development.
机译:人子宫不是一个安静的托儿所。至少有三分之一的婴儿因基因突变和染色体异常而导致健康问题。胎儿还容易受到破坏性外界压力的损害,人们对此知之甚少。在《起源》中,记者安妮·墨菲·保罗(Annie Murphy Paul)回顾了出生前经历影响我们晚年健康的证据。保罗叙述了二十世纪中叶的丑闻,涉及向孕妇使用的两种药物,这使生物医学界意识到胎儿可能对对成年人无害的药物敏感。沙利度胺被规定用于晨吐,并在严格测试所有可能发生的药物之前被批准用于临床,导致肢体发育异常。

著录项

  • 来源
    《Nature》 |2010年第7320期|p.34|共1页
  • 作者

    Michael Sargent;

  • 作者单位

    National Institute for Medical Research, Mill Hill, London;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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