Blood-vessel cells turn to bone

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Blood-vessel cells turn to bone

机译：血管细胞转向骨骼

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In the rare disease fibrodysplasia ossificans progressiva (FOP), a mutation in the Alk2 gene results in the formation of bone in soft tissues. Now researchers show that the bone cells derive from others that form the inner lining of blood vessels, called endothelial cells. These become stem-like cells before re-differentiating into bone. This process could be important in normal tissue repair, suggest Damian Medici at Harvard Medical School and Bjom Olsen at the Harvard School of Dental Medicine, both in Boston, Massachusetts, and their colleagues.

机译：在罕见的进展性骨化性纤维增生症（FOP）中，Alk2基因的突变导致软组织中骨的形成。现在研究人员表明，骨细胞来源于形成血管内壁的其他细胞，称为内皮细胞。它们在重新分化为骨之前成为干细胞样细胞。位于马萨诸塞州波士顿的哈佛医学院的达米安·美第奇（Damian Medici）和哈佛牙科医学院的比约姆·奥尔森（Bjom Olsen）认为，这一过程对于正常的组织修复可能很重要。

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《Nature》 |2010年第7323期|p.479|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. The effect of zinc on endothelium-dependent relaxation of blood-vessels and on the ultrastructure of endothelial cells under immobilization stress. [J] . Kusleikaite M, Stonkus S, Kusleika S Journal of trace elements in medicine and biology: Organ of the Society for Minerals and Trace Elements (GMS) . 2003,第3期

机译：锌对固定应力下血管内皮依赖性舒张作用和内皮细胞超微结构的影响。
2. Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells [J] . Christopher S. Chen, Grace L. Lin, Jeroen Eyckmans Biology Open . 2012,第11期

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3. Consideration of Bone Regeneration Effect of Stem Cells: Comparison of Bone Regeneration between Bone Marrow Stem Cells and Adipose-Derived Stem Cells [J] . HanD.S., ChangH.K., KimK.R., The Journal of craniofacial surgery . 2014,第1期

机译：考虑干细胞的骨再生作用：骨髓干细胞与脂肪干细胞之间的骨再生比较
4. Regeneration of Bone Mass and Bone Quality around Implant with Grooves for Aligning Bone Cells in Rabbit Hindlimb Bones [C] . Takuya Ishimoto, Kentaro Kawata, Takashi Sakai, THERMEC 2011;International conference on processing manufacturing of advanced materials . 2012

机译：用槽对齐兔子后肢骨骼中骨细胞的植入物周围骨质量和骨质量的再生
5. Tissue and Molecular Impact of Modeled Microgravity on Bone Remodeling and Analysis of Tissue Engineering on Bone Tissue and the Relationship of Fluid Movement in Modeled Microgravity on Adult Retinal Pigmented Epithelial Cells and Bone Cells. [D] . Mann, Vivek. 2017

机译：微重力对骨骼重塑的组织和分子影响以及对骨组织的组织工程分析以及微重力对成年视网膜色素上皮细胞和骨细胞的流体运动的关系。
6. A Case of Ligature of the Left Common Carotid Artery wounded by a Fish-bone which had penetrated the Pharynx; with Remarks and an Appendix containing Forty-five Cases of Wounds of Blood-vessels by Foreign Bodies [O] . Walter Rivington 1886

机译：左颈总动脉结扎一例鱼骨穿入咽部受伤的病例；带有备注的附录和包含四十五个外国机构受伤的血管的附录
7. The Blood-vessels of the Middle Ear, in Relation to the Development of the Small Ear-bones and their Muscles. (A preliminary report) [O] . Denjiro Nabeya 1923

机译：中耳的血管，与小耳骨和肌肉的开发相关。（初步报告）

Blood-vessel cells turn to bone

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