A score for membrane fusion

Ruth N. Collins; Joshua Zimmerberg

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A score for membrane fusion

机译：膜融合得分

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Molecules in living organisms are constantly being replaced, yet cellular structures can maintain their identity for a lifetime1. About half of all biological processes involve membrane proteins, which must be delivered, and eventually removed, with great accuracy to regulate the constancy of structural identity. This delivery and removal is mediated by the membrane-bound organelles of eukaryotic cells, which communicate with each other by budding off vesicles and other transport packages, which travel to, and fuse with, target membranes. The organization and regulation of membrane-fusion reactions, then, are crucial for virtually every membrane-bound biological process.

机译：生命有机体中的分子不断被替换，但是细胞结构可以维持其一生的身份1。在所有生物过程中，大约有一半涉及膜蛋白，必须高度精确地调节膜结构蛋白的结构，以保证结构一致性。这种传递和去除是由真核细胞的膜结合细胞器介导的，这些细胞器通过从囊泡和其他运输包装中萌芽而相互连通，而运输至目标膜并与之融合。因此，膜融合反应的组织和调节对于几乎每个膜结合的生物过程都至关重要。

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《Nature》 |2009年第25期|1065-1066|共2页
作者
Ruth N. Collins; Joshua Zimmerberg;
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. Full-length trimeric influenza virus hemagglutinin II membrane fusion protein and shorter constructs lacking the fusion peptide or transmembrane domain: Hyperthermostability of the full-length protein and the soluble ectodomain and fusion peptide make significant contributions to fusion of membrane vesicles [J] . Ratnayake Punsisi U., Ekanayaka E. A. Prabodha, Komanduru Sweta S., Protein Expression and Purification . 2016,第Null期

机译：全长三聚体流感病毒血凝素II膜融合蛋白和缺少融合肽或跨膜结构域的较短构建体：全长蛋白和可溶性胞外域和融合肽的超热稳定性为膜囊泡的融合做出了重要贡献
2. pH-dependent vesicle fusion induced by the ectodomain of the human immunodeficiency virus membrane fusion protein gp41: Two kinetically distinct processes and fully-membrane-associated gp41 with predominant beta sheet fusion peptide conformation [J] . Ratnayake Punsisi U., Sackett Kelly, Nethercott Matthew J., Biochimica et biophysica acta. Biomembranes . 2015,第1aPta2期

机译：人类免疫缺陷病毒膜融合蛋白gp41胞外域诱导的pH依赖性囊泡融合：两个动力学上不同的过程以及具有主要β片层融合肽构象的全膜相关gp41
3. Folded Monomers and Hexamers of the Ectodomain of the HIV gp41 Membrane Fusion Protein: Potential Roles in Fusion and Synergy Between the Fusion Peptide, Hairpin, and Membrane-Proximal External Region [J] . Banerjee Koyeli, Weliky David P. Biochemistry . 2014,第46期

机译：折叠的单体和六种致寡聚蛋白的六聚体：融合肽，发夹和膜 - 近端外部区域的融合和协同作用的潜在作用
4. P-Score: Performance Aligned Normalization and an Evaluation in Score-Level Multi-Biometric Fusion [C] . Naser Damer, Fadi Boutros, Philipp Terhörst, European Signal Processing Conference . 2018

机译：P分数：性能对齐归一化和分数级多生物特征融合的评估。
5. Solid-State Nuclear Magnetic Resonance Studies of the Structures, Membrane Locations, Cholesterol Contact, and Membrane Motions of Membrane-Associated HIV Fusion Peptide (HFP). [D] . Jia, Lihui. 2017

机译：固态核磁共振研究的结构，膜位置，胆固醇接触和膜相关的HIV融合肽（HFP）的膜运动。
6. Full-Length Trimeric Influenza Virus Hemagglutinin II Membrane Fusion Protein and Shorter Constructs Lacking the Fusion Peptide or Transmembrane Domain: Hyperthermostability of the Full-Length Protein and the Soluble Ectodomain and Fusion Peptide Make Significant Contributions to Fusion of Membrane Vesicles [O] . Punsisi U. Ratnayake, E. A. Prabodha Ekanayaka, Sweta S. Komanduru, -1

机译：全长三聚体流感病毒血凝素II膜融合蛋白和较短的构建体缺乏融合肽或跨膜结构域：全长蛋白的超热稳定性以及可溶性Ectodomain和融合肽为膜囊融合提供了重要作用。
7. Full-length trimeric influenza virus hemagglutinin II membrane fusion protein and shorter constructs lacking the fusion peptide or transmembrane domain: Hyperthermostability of the full-length protein and the soluble ectodomain and fusion peptide make significant contributions to fusion of membrane vesicles [O] . Punsisi U. Ratnayake, E.A. Prabodha Ekanayaka, Sweta S. Komanduru, 2016

机译：全长三聚体流感病毒血凝素II膜融合蛋白和缺乏融合肽或跨膜结构域的较短构建体：全长蛋白质的超热性和可溶性突氏蛋白和融合肽对膜囊泡的融合作出显着贡献
8. Effect of Acute Microgravity on Mechanically-Induced Membrane Damage and Membrane-Membrane Fusion Events [R] . 2001

机译：急性微重力对机械诱导膜损伤和膜 - 膜融合事件的影响

A score for membrane fusion

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