Membrane proteins in situ

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Membrane proteins in situ

机译：膜蛋白原位

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X-ray crystal structures have been determined for many membrane proteins, but direct structural information about proteins in their native membrane environment is a rarity. A study combining neutron diffraction, solid-state NMR spectroscopy and molecular dynamics simulations now provides a detailed picture of the structure and hydration of lipid bilayer membranes containing S1-S4 voltage-sensing domains, which are used by membrane proteins to sense and react to changes in membrane voltage.

机译：已经为许多膜蛋白确定了X射线晶体结构，但是在其天然膜环境中有关蛋白的直接结构信息很少。一项结合中子衍射，固态NMR光谱和分子动力学模拟的研究现在提供了包含S1-S4电压感应域的脂质双层膜的结构和水合作用的详细图片，膜蛋白使用该膜来感知变化并对其做出反应膜电压

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《Nature》 |2009年第7272期|386|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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1. In meso in situ In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures [J] . Huang Chia-Ying, Olieric Vincent, Ma Pikyee, Acta crystallographica. Section F, Structural biology communications . 2016,第1期

机译：在MESO的MESO在MESO的原位串行X射线晶体中的溶于溶解和膜蛋白在低温温度下
2. In situ generation of biocompatible amorphous calcium carbonate onto cell membrane to block membrane transport protein - A new strategy for cancer therapy via mimicking abnormal mineralization [J] . Zhu Lin, Wang Ge, Shi Weike, Journal of Colloid and Interface Science . 2019,第期

机译：原位生成生物相容性无定形碳酸钙，在细胞膜上阻断膜转运蛋白 - 通过模拟异常矿化的癌症治疗的新策略
3. In Situ Monitoring of Membrane Protein Insertion into Block Copolymer Vesicle Membranes and Their Spreading via Potential-Assisted Approach [J] . Garakani Tayebeh Mirzaei, Liu Zhanzhi, Glebe Ulrich, ACS applied materials & interfaces . 2019,第32期

机译：原位监测膜蛋白插入嵌段共聚物囊泡膜及其通过潜在辅助方法的扩散
4. An AFM Method for in situ Probing Membrane Proteins under Physiological Condition [C] . Guangyong Li, Ning Xi, Ho-Yin Chan IEEE Conference on Nanotechnology . 2006

机译：在生理条件下原位探测膜蛋白的AFM方法
5. Biophysical studies of integral membrane proteins: 1. A segmented approach to determine the three-dimensional structures of integral membrane proteins 2. Thermal denaturation studies of bovine rhodopsin. [D] . Katragadda, Madan. 2003

机译：整体膜蛋白的生物物理研究：1.确定整体膜蛋白的三维结构的分段方法。2.牛视紫红质的热变性研究。
6. Sequencing of proteins from two-dimensional gels by using in situ digestion and transfer of peptides to polyvinylidene difluoride membranes: application to proteins associated with sensitization in Aplysia. [O] . T E Kennedy, M A Gawinowicz, A Barzilai, 1988

机译：通过使用原位消化和将肽转移到聚偏二氟乙烯膜上的二维凝胶对蛋白质进行测序：在海藻中与致敏相关的蛋白质上的应用。
7. Sequencing of proteins from two-dimensional gels by using in situ digestion and transfer of peptides to polyvinylidene difluoride membranes: application to proteins associated with sensitization in Aplysia. [O] . Kennedy, T E, Gawinowicz, M A, Barzilai, A, 1988

机译：通过使用原位消化和将肽转移到聚偏二氟乙烯膜上的二维凝胶对蛋白质进行测序：在海藻中与致敏相关的蛋白质上的应用。

Membrane proteins in situ

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