A first for vitamins

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A first for vitamins

机译：维生素第一

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The discovery of a vitamin attached to adenosine triphosphate (ATP), the molecule that fuels biochemical reactions, has taken researchers by surprise. Lucien Bettendorff at the University of Liege in Belgium and his colleagues report that vitamin Bl, or thiamine, occurs naturally in complex with ATP — the first vitamin known to do so. The researchers found that the bacterium Escherichia coli produces the complex when starved of glucose.

机译：研究人员惊讶地发现，维生素附有三磷酸腺苷（ATP）这一促进生化反应的分子。比利时列日大学的Lucien Bettendorff和他的同事报告说，维生素B1或硫胺素与ATP天然复合存在，后者是已知的第一种维生素。研究人员发现，缺乏葡萄糖时，大肠杆菌会产生这种复合物。

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《Nature》 |2007年第7132期|p.112|共1页
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收录信息美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2 [J] . Chu PH, Huang TY, Williams J, Proceedings of the National Academy of Sciences of the United States of America . 2006,第51期

机译：单独使用纯化的维生素K环氧还原酶足以将维生素K环氧转化为维生素K，并将维生素K转化为维生素KH2
2. Vitamin D supplements appropriate for preventing osteoporosis? - Vitamin D supplements only in case of deficiency and as a partial aspect of osteoporosis prevention [Vitamin-D-Supplementation zur Osteoporose-Pr?vention sinnvoll? - Vitamin D nur bei Mangel und als Teilaspekt der Osteoporose-Prophylaxe] [J] . ZittermannA. DMW: Deutsche Medizinische Wochenschrift . 2014,第9期

机译：维生素D补充剂是否适合预防骨质疏松症？ -仅在缺乏维生素D并作为预防骨质疏松症的一部分时才补充维生素D [预防骨质疏松症的维生素D补充剂有用吗？ -仅在缺乏维生素D和预防骨质疏松症的情况下使用维生素D
3. No correlation between vitamin D and 137 diseases - Vitamin D: A long way to go to clinical practice [Keine klare Korrelation zwischen Vitamin D und 137 Krankheiten - Vitamin D: ein weiter Weg zur Klinik] [J] . ZieglerA., LehnertH. DMW: Deutsche Medizinische Wochenschrift . 2014,第30期

机译：维生素D与137种疾病之间没有相关性-维生素D：临床实践还有很长的路要走[维生素D与137种疾病之间没有明显的相关性-维生素D：通往临床实践的长路要走]
4. Synthesis and Vitamin D Receptor Affinity of 16-Oxa Vitamin D3Derivatives-1 [C] . Ogami Mayu, Ibe Kouta, Yamada Takeshi 日本化学会春季年会 . 2020

机译：16-OXA维生素D3远序列-1的合成和维生素D受体亲和力-1
5. The effect of vitamin D2, vitamin D3 or vitamin D2 in mushroom powder supplements on broad gene expression in human white blood cells. [D] . Feigert, Caroline Elizabeth. 2014

机译：蘑菇粉中的维生素D2，维生素D3或维生素D2对人白细胞中广泛基因表达的影响。
6. Correction for Chu et al. Purified vitamin K epoxide reductase alone is sufficient for conversion of vitamin K epoxide to vitamin K and vitamin K to vitamin KH2 [O] . 2014

机译：对Chu等人的修正仅纯化的维生素K环氧还原酶就足以将维生素K环氧转化为维生素K并将维生素K转化为维生素KH2
7. Six practical diets were formulated to contain 2.6 (the basal diet), 48.9, 95.5, 189.83, 382.4, 779.53 mg/kg vitamin C diet. After 8 weeks of feeding, growth performance, antioxidant status, and innate immunity of juvenile pufferfish were analyzed. Results showed that specific growth rate and protein efficiency ratio in fish fed diets supplemented with vitamin C were significantly higher than in fish fed the control diet. Dietary vitamin C significantly up-regulated the expression levels of growth hormone receptors and Insulin-like growth factor. Blood cell numbers and respiratory burst activity were enhanced in fish fed vitamin C diet. Serum alkaline phosphatase, glutamic-pyruvic transaminase, and glutamic-oxaloacetic transaminase activity were significantly influenced by the dietary vitamin C levels. Fish fed diets supplemented with vitamin C showed increased hepatic superoxide dismutase, glutathione peroxidase, and catalase activity, but decreased malondialdehyde activity. In addition, we found that dietary vitamin C can significantly up-regulate the expression levels of immune-related genes (HSP70, HSP90, BAFF, TNF-α and IL-6) in liver. These results indicate that dietary vitamin C can significantly influence growth performance, antioxidant status, and innate immunity of pufferfish. [O] . Cheng C-H, Liang H-Y., Guo Z-X., 2017

机译：配制了六种实用饮食，分别含有2.6（基础饮食），48.9、95.5、189.83、382.4、779.53 mg / kg维生素C饮食。喂食8周后，分析了幼崽河豚的生长性能，抗氧化剂状态和先天免疫力。结果表明，补充维生素C的鱼饲料的比生长速率和蛋白质效率比显着高于对照组的鱼。饮食中的维生素C显着上调了生长激素受体和胰岛素样生长因子的表达水平。喂鱼的维生素C饮食可提高血细胞数量和呼吸爆发活性。饮食中的维生素C水平显着影响血清碱性磷酸酶，谷氨酸-丙酮酸转氨酶和谷氨酸-草酰乙酸转氨酶的活性。补充维生素C的鱼饲料日粮中肝超氧化物歧化酶，谷胱甘肽过氧化物酶和过氧化氢酶活性增加，但丙二醛活性降低。此外，我们发现饮食中的维生素C可以显着上调肝脏中免疫相关基因（HSP70，HSP90，BAFF，TNF-α和IL-6）的表达水平。这些结果表明，饮食中的维生素C可以显着影响河豚的生长性能，抗氧化状态和先天免疫力。

A first for vitamins

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