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Unravelling hepatitis C virus replication from genome to function

机译:阐明丙型肝炎病毒从基因组到功能的复制

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摘要

Since the discovery of the hepatitis C virus over 15 years ago, scientists have raced to develop diagnostics, study the virus and find new therapies. Yet virtually every attempt to dissect this pathogen has met with roadblocks that impeded progress. Its replication was restricted to humans or experimentally infected chimpanzees, and efficient growth of the virus in cell culture failed until very recently. Nevertheless hard-fought progress has been made and the first wave of antiviral drugs is entering clinical trials.
机译:自从15年前发现丙型肝炎病毒以来,科学家们竞相开发诊断方法,研究该病毒并找到新的疗法。但是,实际上,每次剖析这种病原体的尝试都遇到了阻碍发展的障碍。它的复制仅限于人类或实验感染的黑猩猩,并且病毒在细胞培养中的有效生长一直持续到最近。然而,已经取得了艰苦的努力,抗病毒药物的第一波正在进入临床试验。

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