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The cost of living

机译:生活费用

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摘要

The 1960s was an important time for mito-chondrial research, which saw many sig-nificant and enduring advances. During this period, Peter Mitchell developed the chemiosmotic proposal―the coupling of biological electron transfer to ATP synthesis. Although it ultimately won Mitchell a Nobel Prize, his work was highly controversial, and it was more than a decade before his ideas were accepted widely, leading some researchers to claim prior ownership of key elements of the ideas that still persist today. The fact that mitochondria are central to the efficient provision of energy for eukary-otic cells is undisputed. It is generally accepted that the early and energetically inefficient eukaryotic cell was invaded more than a billion years ago by a bacterium containing a much more efficient system for utilizing available energy sources―the oxygen-consuming respiratory chain. The majority of the bacterial genetic information was subsequently transferred to the nucleus, transforming the bacterial symbionts into slave mitochondrial organelles.
机译:1960年代是线粒体研究的重要时期,它取得了许多重大而持久的进步。在此期间,彼得·米切尔(Peter Mitchell)提出了化学渗透的提案-生物电子转移与ATP合成的耦合。尽管它最终获得了米切尔的诺贝尔奖,但他的工作引起了很大争议,并且十多年来他的想法被广泛接受,导致一些研究人员要求对这些想法的关键要素拥有先前的所有权,直到今天仍然坚持。线粒体对于真核细胞有效提供能量至关重要,这一事实是无可争议的。人们普遍认为,早期和能量效率低下的真核细胞是在十亿年前被一种细菌入侵的,这种细菌含有一种更为有效的系统,可以利用现有的能源-耗氧的呼吸链。随后,大多数细菌遗传信息被转移到细胞核,将细菌共生体转化为奴隶线粒体细胞器。

著录项

  • 来源
    《Nature》 |2003年第6923期|p.583|共1页
  • 作者

    Peter Rich;

  • 作者单位

    Department of Biology, University College London, Gower Street, London WC1E6BT, UK;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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