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MicroRNA is here to stay

机译:MicroRNA待在这里

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摘要

The first glimpse of the wave was more than a decade ago, when a strange form of gene regulation was described that involved the binding of one RNA molecule to another. Then last year, with reports that there are hundreds of small RNAs in the genome, it came into view. There was the possibility that a whole layer of gene regulation involving very small RNA molecules called microRNAs had been overlooked for 40 years. But still there were doubts as to the importance of microRNAs ―the wave might yet turn out to be scarcely a ripple, let alone a tsunami. With the description by Palatnik et al. of the role of microRNAs in controlling plant development (page 257 of this issue), and other new publications reporting important functions in animals, the wave looks very real ― and big.
机译:大约在十多年前,人们就首次看到了这一浪潮,当时描述了一种奇怪的基因调节形式,涉及一个RNA分子与另一个RNA分子的结合。去年,据报道,基因组中有数百个小RNA。 40年以来,有可能忽略了涉及非常小的RNA分子(称为microRNA)的整个基因调控层。但是,对于微RNA的重要性仍然存在疑问-这一波可能尚未证明是涟漪,更不用说海啸了。随着Palatnik等人的描述。关于microRNA在控制植物发育中的作用(本期第257页)以及其他报道了动物重要功能的新出版物,这一浪潮看起来非常真实而且意义重大。

著录项

  • 来源
    《Nature》 |2003年第6955期|p.244-245|共2页
  • 作者

    Philip N. Benfey;

  • 作者单位

    Department of Biology, Box 91000, Duke University, Durham, North Carolina 27708, USA;

  • 收录信息 美国《科学引文索引》(SCI);美国《工程索引》(EI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 自然科学总论;
  • 关键词

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