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Plant recognition of symbiotic bacteria requires two LysM receptor-like kinases

机译:植物对共生细菌的识别需要两个LysM受体样激酶

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Although most higher plants establish a symbiosis with arbuscular mycorrhizal fungi, symbiotic nitrogen fixation with rhizobia is a salient feature of legumes. Despite this host range difference, mycorrhizal and rhizobial invasion shares a common plant-specified genetic programme controlling the early host interaction. One feature distinguishing legumes is their ability to perceive rhizobial-specific signal molecules. We describe here two LysM-type serine/threonine receptor kinase genes, NFR1 and NFR5, enabling the model legume Lotus japonicus to recognize its bacterial microsymbiont Mesorhizobium loti. The extracellular domains of the two transmembrane kinases resemble LysM domains of peptidoglycan- and chitin-binding proteins, suggesting that they may be involved directly in perception of the rhizobial lipochitin-oligosaccharide signal. We show that NFR1 and NFR5 are required for the earliest physiological and cellular responses to this lipochitin-oligosaccharide signal, and demonstrate their role in the mechanism establishing susceptibility of the legume root for bacterial infection. [References: 47]
机译:尽管大多数高等植物与丛枝菌根真菌共生,但根瘤菌共生固氮是豆科植物的显着特征。尽管宿主范围存在差异,但菌根和根瘤菌入侵具有共同的植物特异性遗传程序,可控制宿主早期的相互作用。区分豆科植物的一个特征是它们感知根瘤菌特异性信号分子的能力。我们在这里描述两个LysM型丝氨酸/苏氨酸受体激酶基因,NFR1和NFR5,使模型豆科植物日本莲能够识别其细菌微共生介孢菌。两种跨膜激酶的胞外域类似于肽聚糖和几丁质结合蛋白的LysM域,表明它们可能直接参与了对根瘤菌脂多糖寡糖信号的感知。我们显示NFR1和NFR5是必需的,对这种脂壳素-寡糖信号的最早的生理和细胞反应,并证明了它们在建立豆科植物根系对细菌感染的敏感性中的作用。 [参考:47]

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