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首页> 外文期刊>Osaka City Medical Journal >Splenic Metastasis of Hepatocellular Carcinoma
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Splenic Metastasis of Hepatocellular Carcinoma

机译：肝细胞癌的脾转移

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A 76 year-old man, who underwent central bisegmentectomy of the liver, transcatheter arterial chemoembolization, and radiofrequency ablation for chronic hepatitis C virus-related hepatocellular carcinoma (HCC), was found to have a 3 cm mass in the spleen and a 2 cm mass in the liver by computed tomography in January 2003. As both tumors were adjacent, a diagnosis of HCC with splenic infiltration was made. In February 2003, transcatheter arterial chemoembolization and splenic arterial chemo-infusion were performed. However, the splenic tumor increased to 5 cm with slight enhancement on contrast-enhanced computed tomography performed 6 months later, while the hepatic tumor had no enhancement. Limited resection of the liver with splenectomy was performed in October 2003. Macroscopically, the splenic tumor showed infiltrative growth without a capsule while the hepatic tumor showed complete necrosis within its capsule. The splenic tumor was limited to the splenic parenchyma. Histologic examination revealed that the splenic tumor was poorly differentiated HCC, leading to the diagnosis of splenic metastasis. The patient is doing well 17 months after surgery without recurrence. One should perform surgery for splenic metastasis of HCC without hesitation whenever possible.
机译：一名76岁的男子因进行慢性丙型肝炎病毒相关的肝细胞癌（HCC）接受了肝脏中央双段切除术，经导管动脉化学栓塞和射频消融治疗，发现其脾脏肿块3厘米，肿块2厘米于2003年1月通过计算机断层扫描在肝脏中发现肿块。由于两个肿瘤相邻，因此诊断为脾脏浸润的HCC。 2003年2月，进行了经导管动脉化学栓塞和脾动脉化学灌注。然而，在6个月后进行的对比增强计算机断层扫描中，脾肿瘤增至5 cm，并稍有增强，而肝肿瘤则无增强。 2003年10月进行了脾切除术，对肝脏进行了有限的切除。从宏观上看，脾脏肿瘤浸润性生长，没有包膜，而肝肿瘤在其囊膜中完全坏死。脾肿瘤仅限于脾实质。组织学检查显示，脾脏肿瘤的HCC分化较差，可诊断为脾脏转移。术后17个月，患者恢复良好，无复发。只要有可能，就应该毫不犹豫地进行肝癌脾转移的手术。

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