...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Pediatric Surgery International >Successful treatment of severe refractory anastomotic stricture in an infant after esophageal atresia repair by endoscopic balloon dilation combined with systemic administration of dexamethasone
【24h】

Successful treatment of severe refractory anastomotic stricture in an infant after esophageal atresia repair by endoscopic balloon dilation combined with systemic administration of dexamethasone

机译：内镜球囊扩张联合全身性地塞米松治疗食管闭锁修复婴儿严重难治性吻合口狭窄成功

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A boy with a history of esophageal atresia repair received an esophagoesophagostomy at 14 months for a severe refractory anastomotic stricture, which had already required repeated balloon dilation with intralesional dexamethasone injection. Anastomotic leakage and stricture was again evident after the second surgery, and the patient underwent five procedures of balloon dilations with intralesional dexamethasone injection. Dysphagia was persistent and the patient required dilation every 2–3 weeks. After the sixth dilation, the patient was given 1 mg/kg per day of dexamethasone i.v. for 3 days. Dexamethasone i.v. was tapered during the following 3 days and finished at day 6. A week later, endoscopic findings showed an apparent improvement in the stricture. Another dilation was followed by 1 mg/kg per day dexamethasone i.v. for 7 days, and 0.75 kg/mg per day oral dexamethasone for another 7 days. The stricture improved completely and the anastomosis was patent after the second dilation. The patient is doing well without dysphagia and has not required additional dilation for over 18 months after the last dilation. Balloon dilation in combination with systemic dexamethasone administration may be an effective treatment that could substitute invasive techniques including surgical manipulation for severe refractory strictures.
机译：有食管闭锁修复史的男孩在14个月因严重的难治性吻合口狭窄而接受了食管食管造口术，这已经需要通过病灶内地塞米松注射反复进行球囊扩张术。第二次手术后再次出现吻合口漏和狭窄，该患者接受了病灶内地塞米松注射五次球囊扩张手术。吞咽困难持续存在，患者每2-3周需要扩张一次。第六次扩张后，每天给患者静脉注射地塞米松1 mg / kg。 3天。地塞米松i.v.在接下来的3天中逐渐变细，并在第6天结束。一周后，内窥镜检查结果显示狭窄明显改善。另一次扩张是每天地塞米松静脉滴注1 mg / kg。持续7天，每天口服0.75毫克/毫克地塞米松，持续7天。狭窄完全改善，在第二次扩张后吻合获得专利。患者身体状况良好，没有吞咽困难，并且在最后一次扩张后的18个月内不需要额外扩张。球囊扩张术与全身性地塞米松联合给药可能是一种有效的治疗方法，可以代替侵入性技术，包括手术治疗严重的难治性狭窄。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号