Cationic Lipid-Coated Gold Nanoparticles as Efficient and Non-Cytotoxic Intracellular siRNA Delivery Vehicles

Won Ho Kong; Ki Hyun Bae; Sung Duk Jo; Jee Seon Kim; Tae Gwan Park

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Cationic Lipid-Coated Gold Nanoparticles as Efficient and Non-Cytotoxic Intracellular siRNA Delivery Vehicles

机译：阳离子脂质涂层金纳米粒子作为高效和无细胞毒性的细胞内siRNA传递载体。

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Cationic lipid-coated gold nanoparticles were developed for efficient intracellular delivery of therapeutic siRNA.

机译：阳离子脂质包覆的金纳米颗粒被开发用于有效的细胞内递送治疗性siRNA。

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来源
《Pharmaceutical Research》 |2012年第2期|p.362-374|共13页
作者
Won Ho Kong; Ki Hyun Bae; Sung Duk Jo; Jee Seon Kim; Tae Gwan Park;
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作者单位

Department of Biological Sciences, Graduate School of Nanoscience &amp Technology Korea Advanced Institute of Science &amp Technology, Daejeon, 305-701, South Korea;

Department of Biological Sciences, Graduate School of Nanoscience &amp Technology Korea Advanced Institute of Science &amp Technology, Daejeon, 305-701, South Korea;

Department of Biological Sciences, Graduate School of Nanoscience &amp Technology Korea Advanced Institute of Science &amp Technology, Daejeon, 305-701, South Korea;

Department of Biological Sciences, Graduate School of Nanoscience &amp Technology Korea Advanced Institute of Science &amp Technology, Daejeon, 305-701, South Korea;

Department of Biological Sciences, Graduate School of Nanoscience &amp Technology Korea Advanced Institute of Science &amp Technology, Daejeon, 305-701, South Korea;

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原文格式 PDF
正文语种 eng
中图分类
关键词
cancer therapy; cationic lipid; delivery system; gold nanoparticle; siRNA;

机译：癌症治疗;阳离子脂质;递送系统;金纳米颗粒;siRNA;

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专利

1. Cationic lipid-coated gold nanoparticles as efficient and non-cytotoxic intracellular siRNA delivery vehicles. [J] . Won Ho Kong, Ki Hyun Bae, Sung Duk Jo, Pharmaceutical research . 2012,第2期

机译：阳离子脂质包覆的金纳米颗粒作为有效且无细胞毒性的细胞内siRNA传递载体。
2. Amine-functionalized gold nanoparticles as non-cytotoxic and efficient intracellular siRNA delivery carriers. [J] . Lee SH, Bae KH, Kim SH, International Journal of Pharmaceutics . 2008,第1期

机译：胺功能化的金纳米颗粒作为无细胞毒性和有效的细胞内siRNA传递载体。
3. Modified gold nanoparticles for intracellular delivery of anti-liver cancer siRNA [J] . Shaat Hanan, Mostafa Amany, Moustafa Moustafa, International Journal of Pharmaceutics . 2016,第1a2期

机译：用于细胞内递送抗肝癌siRNA的改性金纳米粒子
4. Combinatorial cationic lipid-like nanoparticles for efficient intracellular cytotoxic protein delivery [C] . Ming Wang, Qiaobing Xu 2014 40th Annual Northeast Bioengineering Conference . 2014

机译：组合阳离子脂质样纳米颗粒，可有效递送细胞内细胞毒性蛋白
5. Development of Gold Nanoparticle towards Radioenhancement Therapy, Renal Clearance, siRNA Delivery and Light-Controlled Gene Silencing. [D] . Wang, Jianxin. 2017

机译：金纳米粒子在放射增强治疗，肾脏清除，siRNA递送和光控基因沉默方面的发展。
6. Efficient delivery of NF-κB siRNA to human retinal pigment epithelial cells with hyperbranched cationic polysaccharide derivative-based nanoparticles [O] . Zhenzhen Liu, Haijun Gong, Rui Zeng, 2015

机译：基于超支化阳离子多糖衍生物的纳米粒子有效地将NF-κBsiRNA传递至人视网膜色素上皮细胞
7. Bioreducible Cationic Polymer-Based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic siRNA Delivery to Primary Human Brain Cancer Cells [O] . Kristen L. Kozielski, Stephany Y. Tzeng, Bolivia A. Hurtado De Mendoza, 2014

机译：基于生物的阳离子聚合物的纳米粒子用于高效和环境触发的细胞质siRNA递送给原发性人脑癌细胞

Cationic Lipid-Coated Gold Nanoparticles as Efficient and Non-Cytotoxic Intracellular siRNA Delivery Vehicles

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