Chondrogenic Priming Adipose-Mesenchymal Stem Cells for Cartilage Tissue Regeneration

Nathaniel S. Hwang; Sung Gap Im; Patrick B. Wu; David A. Bichara; Xing Zhao; Mark A. Randolph; Robert Langer; Daniel G. Anderson

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Chondrogenic Priming Adipose-Mesenchymal Stem Cells for Cartilage Tissue Regeneration

机译：软骨启动脂肪间充质干细胞用于软骨组织再生

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Purpose Chondrocytes lose their ability to produce cartilaginous matrix during multiplication in culture through repeated passages, resulting in inferior tissue phenotype. To overcome the limited amount of primary chondrocytes, we aimed to determine the optimal culture condition for in vitro/in vivo cartilage regeneration using human adipose-derived mesenchymal stem cells (AMSCs).

机译：目的软骨细胞在培养过程中通过反复传代繁殖而丧失产生软骨基质的能力，从而导致劣质的组织表型。为了克服有限数量的原代软骨细胞，我们旨在确定使用人脂肪来源的间充质干细胞（AMSC）进行体外/体内软骨再生的最佳培养条件。

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《Pharmaceutical Research》 |2011年第6期|p.1395-1405|共11页
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Nathaniel S. Hwang; Sung Gap Im; Patrick B. Wu; David A. Bichara; Xing Zhao; Mark A. Randolph; Robert Langer; Daniel G. Anderson;
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1. Chondrogenic priming adipose-mesenchymal stem cells for cartilage tissue regeneration. [J] . Hwang NS, Im SG, Wu PB, Pharmaceutical research . 2011,第6期

机译：软骨致敏的脂肪-间充质干细胞用于软骨组织再生。
2. An In Vitro Bone Tissue Regeneration Strategy Combining Chondrogenic and Vascular Priming Enhances the Mineralization Potential of Mesenchymal Stem Cells In Vitro While Also Allowing for Vessel Formation [J] . Freeman Fiona E., Haugh Matthew G., McNamara Laoise M. Tissue engineering, Part A . 2015,第7a8期

机译：软骨和血管灌注相结合的体外骨组织再生策略增强了间充质干细胞的体外矿化潜力，同时也允许血管形成
3. Donor-Matched Comparison of Chondrogenic Potential of Equine Bone Marrow- and Synovial Fluid-Derived Mesenchymal Stem Cells: Implications for Cartilage Tissue Regeneration [J] . Zayed Mohammed, Caniglia Christopher, Misk Nabil, Frontiers in Veterinary Science . 2017,第7期

机译：供体匹配的马骨髓和滑液来源的间充质干细胞的软骨生成潜力的比较：对软骨组织再生的影响。
4. PRIMING OF SYNOVIUM-DERIVED MESENCHYMAL STEM CELLS FOR CARTILAGE TISSUE ENGINEERING [C] . Najmuddin Gunja, Jason Fong, Andrea Tan, ASME summer bioengineering conference;SBC2010 . 2010

机译：软骨组织工程的滑膜间充质干细胞的制备
5. Studies of Chondrogenic Dedifferentiation-Reprogrammed Mesenchymal Stem Cells in the Treatment of Cartilage Lesions [D] . Lin, Sien. 2015

机译：软骨去分化重编程间充质干细胞治疗软骨病变的研究
6. Donor-Matched Comparison of Chondrogenic Potential of Equine Bone Marrow- and Synovial Fluid-Derived Mesenchymal Stem Cells: Implications for Cartilage Tissue Regeneration [O] . Mohammed Zayed, Christopher Caniglia, Nabil Misk, 2016

机译：供体匹配的马骨髓和滑液来源的间充质干细胞的软骨生成潜力的比较：对软骨组织再生的影响。
7. Differentiation and derivation of lineage-committed chondroprogenitors and chondrogenic cells from human embryonic stem cells for cartilage tissue engineering and regeneration [O] . TOH WEI SEONG 2010

机译：从人类胚胎干细胞分化和衍生出承袭的软骨生成细胞和软骨生成细胞，用于软骨组织工程和再生

Chondrogenic Priming Adipose-Mesenchymal Stem Cells for Cartilage Tissue Regeneration

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