Assessment of P-glycoprotein Activity in the Blood-Brain Barrier (BBB) Using Near Infrared Fluorescence (NIRF) Imaging Techniques

Ngoc H. On; Fang Chen; Martha Hinton; Donald W. Miller

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Assessment of P-glycoprotein Activity in the Blood-Brain Barrier (BBB) Using Near Infrared Fluorescence (NIRF) Imaging Techniques

机译：使用近红外荧光（NIRF）成像技术评估血脑屏障（BBB）中的P糖蛋白活性

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Purpose To examine functional activity of P-glycoprotein (P-gp) in the blood-brain barrier (BBB) using near infrared fluorescence (NIRF) imaging techniques.

机译：目的使用近红外荧光（NIRF）成像技术检查血脑屏障（BBB）中P糖蛋白（P-gp）的功能活性。

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《Pharmaceutical Research》 |2011年第10期|p.2505-2515|共11页
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Ngoc H. On; Fang Chen; Martha Hinton; Donald W. Miller;
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1. Assessment of P-glycoprotein activity in the Blood-Brain Barrier (BBB) using Near Infrared Fluorescence (NIRF) imaging techniques. [J] . On NH, Chen F, Hinton M, Pharmaceutical research . 2011,第10期

机译：使用近红外荧光（NIRF）成像技术评估血脑屏障（BBB）中的P糖蛋白活性。
2. Blood-brain barrier (BBB) pharmacoproteomics: reconstruction of in vivo brain distribution of 11 P-glycoprotein substrates based on the BBB transporter protein concentration, in vitro intrinsic transport activity, and unbound fraction in plasma and brain in mice. [J] . Uchida Y, Ohtsuki S, Kamiie J, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2011,第2期

机译：血脑屏障（BBB）药动学：基于BBB转运蛋白的浓度，体外固有转运活性以及小鼠血浆和脑中未结合的部分，重建11种P-糖蛋白底物的体内脑分布。
3. Near-infrared fluorescence (NIRF) imaging in breast-conserving surgery: assessing intraoperative techniques in tissue-simulating breast phantoms. [J] . Pleijhuis RG, Langhout GC, Helfrich W, European Journal of Surgical Oncology: The Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology . 2011,第1期

机译：保乳手术中的近红外荧光（NIRF）成像：评估组织模拟乳模中的术中技术。
4. A novel family of diketopiperazines as a tool for the study of transport across the blood-brain barrier (BBB) and their potential use as BBB-shuttles. [C] . Meritxell Teixido, Esther Zurita, Roger Prades American Peptide Symposium . 2009

机译：一种新的Diketopiperazines系列作为研究血脑屏障（BBB）的运输的工具及其作为BBB班车的潜在用途。
5. GenX Inhibits P-glycoprotein and Breast Cancer Resistance Protein Transport Activity and Expression at the Blood-brain Barrier in Sprague-Dawley Rats [D] . Richards, Alicia Carolyn. 2018

机译：GenX抑制Sprague-Dawley大鼠的P-糖蛋白和乳腺癌抗性蛋白转运活性及在血脑屏障的表达
6. Regional P-glycoprotein Activity and Inhibition at the Human Blood-Brain Barrier as Imaged by Positron Emission Tomography [O] . Sara Eyal, Ban Ke, Mark Muzi, -1

机译：通过正电子发射断层扫描成像人血脑屏障的区域对糖蛋白活性和抑制作用
7. Near-infrared fluorescence (NIRF) imaging in breast-conserving surgery:Assessing intraoperative techniques in tissue-simulating breast phantoms [O] . Pleijhuis, R. G., Langhout, G. C., Helfrich, W., 2011

机译：保乳手术中的近红外荧光（NIRF）成像：评估组织模拟乳模中的术中技术

Assessment of P-glycoprotein Activity in the Blood-Brain Barrier (BBB) Using Near Infrared Fluorescence (NIRF) Imaging Techniques

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