Poly (lactide- co -glycolide)-Polymethacrylate Nanoparticles for Intramuscular Delivery of Plasmid Encoding Interleukin-10 to Prevent Autoimmune Diabetes in Mice

Ashwin Basarkar; Jagdish Singh

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Poly (lactide- co -glycolide)-Polymethacrylate Nanoparticles for Intramuscular Delivery of Plasmid Encoding Interleukin-10 to Prevent Autoimmune Diabetes in Mice

机译：聚（丙交酯-共-乙交酯）-聚甲基丙烯酸甲酯纳米颗粒用于肌内递送编码白细胞介素10的质粒，以预防小鼠自身免疫性糖尿病。

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Purpose Determine the efficiency of cationic nanoparticles prepared by blending poly (lactide-co-glycolide; PLGA) and methacrylate copolymer (Eudragit® E100) to deliver a therapeutic gene encoding mouse interleukin-10, in vitro and in vivo.

机译：目的确定通过将聚（丙交酯-共-乙交酯； PLGA）和甲基丙烯酸酯共聚物（E100）共混制备的阳离子纳米粒子在体外和体内传递编码小鼠白介素10的治疗性基因的效率。

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《Pharmaceutical Research》 |2009年第1期|p.72-81|共10页
作者
Ashwin Basarkar; Jagdish Singh;
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1. Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. [J] . Basarkar A, Singh J Pharmaceutical research . 2009,第1期

机译：聚（丙交酯-共-乙交酯）-聚甲基丙烯酸甲酯纳米颗粒用于肌肉内传递编码白介素10的质粒，以预防小鼠自身免疫性糖尿病。
2. Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. [J] . Basarkar A, Singh J Pharmaceutical research . 2009,第10期

机译：聚（丙交酯-共-乙交酯）-聚甲基丙烯酸甲酯纳米颗粒用于肌肉内传递编码白介素10的质粒，以预防小鼠自身免疫性糖尿病。
3. Intramuscular injection of interleukin-10 plasmid DNA prevented autoimmune diabetes in mice [J] . ZHANG Zhen-Lin, SHEN Shui-Xian, LIN Bo, Acta Pharmacologica Sinica . 2003,第8期

机译：肌内注射白介素10质粒DNA可预防小鼠自身免疫性糖尿病
4. PREVENTION OF AUTOIMMUNE DIABETES IN NOD MICE WITH DELIVERY OF IL-4 AND IL-10 PLASMIDS [C] . K.S. Ko, M. Lee, J.J. Koh, International symposium on controlled release of bioactive materials;Consumer diversified products conference . 2001

机译：预防IL-4和IL-10质粒递送的NOD小鼠自身免疫性糖尿病。
5. Chitosan-coated poly(lactide-co-glycolide) nanoparticles for DNA delivery. [D] . Guo, Chunqiang. 2007

机译：脱乙酰壳多糖涂层的聚（丙交酯-共-乙交酯）纳米颗粒用于DNA传递。
6. Preparation characterization cytotoxicity and transfection efficiency of poly (DL-lactide-co-glycolide) and poly (DL-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA [O] . Ashwin Basarkar, Dilip Devineni, Ravi Palaniappan, -1

机译：聚（DL-丙交酯-乙交酯）和聚（DL-乳酸）阳离子纳米粒子的制备表征细胞毒性和转染效率可控制质粒DNA的传递
7. Preparation, characterization, cytotoxicity and transfection efficiency of poly(dl-lactide-co-glycolide) and poly(dl-lactic acid) cationic nanoparticles for controlled delivery of plasmid DNA [O] . A BASARKAR, D DEVINENI, R PALANIAPPAN, 2007

机译：聚（D1-丙交酯 - 共乙酰基）和聚（DL-乳酸）阳离子纳米粒子进行纳康质粒DNA的阳离子纳米粒子的制备，表征，细胞毒性和转染效率

Poly (lactide- co -glycolide)-Polymethacrylate Nanoparticles for Intramuscular Delivery of Plasmid Encoding Interleukin-10 to Prevent Autoimmune Diabetes in Mice

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