Real-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment

Betrouni Nacim; Munck Camille; Bensoltana Wael; Baert Gregory; Dewalle-Vignion Anne-Sophie; Scherpereel Arnaud; Mordon Serge

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Real-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment

机译：腔内光动力疗法的实时光剂量测定：在胸膜间皮瘤治疗中的应用

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摘要

Complete and homogeneous illumination of the target is necessary for the success of a photodynamic therapy (PDT) procedure. In most applications, light dosimetry is done using detectors placed at strategic locations of the target. In this study we propose a novel approach based on the combination of light distribution modeling with spatial localization of the light applicator for real time estimation and display of the applied dose on medical images. The feasibility approach is demonstrated for intrapleural PDT of malignant pleural mesothelioma. (C) 2017 Elsevier B.V. All rights reserved.

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《Photodiagnosis and Photodynamic Therapy》 |2017年第6期|155-161|共7页
作者
Betrouni Nacim; Munck Camille; Bensoltana Wael; Baert Gregory; Dewalle-Vignion Anne-Sophie; Scherpereel Arnaud; Mordon Serge;
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INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France|Lille Univ Hosp, F-59037 Lille, France;

INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France|Lille Univ Hosp, F-59037 Lille, France;

INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France;

INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France;

INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France;

Lille Univ Hosp, F-59037 Lille, France;

INSERM, U1189, 1 Ave Oscar Lambret, F-59037 Lille, France|Lille Univ Hosp, F-59037 Lille, France;

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正文语种 eng
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关键词
Photodynamic therapy; Intra-cavity application; Light distribution modeling; Dosimetry; Real time tracking; Imaging;

机译：光动力疗法;腔内应用;光分布建模;剂量测定;实时跟踪;成像;

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专利

1. Illumination profile characterization of a light device for the dosimetry of intra-pleural photodynamic therapy for mesothelioma [J] . Munck Camille, Mordon Serge, Betrouni Nacim Photodiagnosis and Photodynamic Therapy . 2016,第deca期

机译：用于间皮瘤胸膜内光动力疗法剂量学的照明设备的照明轮廓表征
2. Wedge-shaped applicator for additional light delivery and dosimetry in the diaphragmal sinus during photodynamic therapy for malignant pleural mesothelioma. [J] . van-Veen P, Schouwink JH, Star WM, Physics in medicine and biology. . 2001,第7期

机译：楔形涂抹器可在光动力治疗恶性胸膜间皮瘤期间在additional窦中提供额外的光传输和剂量测定。
3. Intra-cavity Photodynamic Therapy for malignant tumors of the paranasal sinuses: An in vivo light dosimetry study [J] . van Doeveren T. E. M., van Veen R. L. P., van den Boom F., Photodiagnosis and Photodynamic Therapy . 2020,第Deca期

机译：腔内阴光疗法对血管鼻窦恶性肿瘤：体内光剂量测定研究
4. Interstitial photodynamic therapy for primary prostate cancer incorporating real-time treatment dosimetry [C] . Ann Johansson, Johan Axelsson, Johannes Swartling, Conference on Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy . 2007

机译：主要前列腺癌的间质光动力治疗掺入实时治疗剂量测定
5. Light dosimetry for interstitial photodynamic therapy: Application to the treatment of prostatic carcinoma. [D] . Dickey, Dwayne J. 2004

机译：间隙光动力疗法的光剂量法：在前列腺癌治疗中的应用。
6. SmartPDT®: Smartphone enabled real-time dosimetry via satellite observation for daylight photodynamic therapy [O] . Luke J. McLellan, Marco Morelli, Emilio Simeone, -1

机译：SmartPDT®：通过卫星观察通过智能手机实现的实时剂量测定用于日光动力疗法
7. Real-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment [O] . Betrouni, Nacim, Munck, Camille, Bensoltana, Wael, 2017

机译：腔内光动力疗法的实时光剂量测定：在胸膜间皮瘤治疗中的应用
8. Light Dosimetry Model for Photodynamic Therapy Treatment Planning [R] . Grossweiner, L. I. 1991

机译：光动力疗法治疗计划的光剂量学模型

Real-time light dosimetry for intra-cavity photodynamic therapy: Application for pleural mesothelioma treatment

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