Fluorescence spectroscopy as a tool to in vivo discrimination of distinctive skin disorders

Maciel Vitoria Helena; Correr Wagner Rafael; Kurachi Cristina; Bagnato Vanderlei Salvador; Souza Cacilda da Silva

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Fluorescence spectroscopy as a tool to in vivo discrimination of distinctive skin disorders

机译：荧光光谱法作为体内区分独特皮肤疾病的工具

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摘要

Background: Fast and non-invasive analytical methods, as in fluorescence spectroscopy, have potential applications to detect modifications of biochemical and morphologic properties of malignant tissues. In this study, we propose to analyze the fluorescence spectra using k-Nearest Neighbours algorithm (k-NN) and ratio of the fluorescence intensity (FI) to differentiate skin disorders of distinctive etiologies and morphologies.

机译：背景：快速且非侵入性的分析方法（如荧光光谱法）在检测恶性组织的生物化学和形态学特性的改变方面具有潜在的应用前景。在这项研究中，我们建议使用k最近邻算法（k-NN）和荧光强度比（FI）来分析荧光光谱，以区分出独特病因和形态的皮肤疾病。

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来源
《Photodiagnosis and Photodynamic Therapy》 |2017年第9期|45-50|共6页
作者
Maciel Vitoria Helena; Correr Wagner Rafael; Kurachi Cristina; Bagnato Vanderlei Salvador; Souza Cacilda da Silva;
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作者单位

Univ Sao Paulo, Inst Phys Sao Carlos, Av Trabalhador Sao Carlense, BR-13566590 Sao Carlos, SP, Brazil|Univ Sao Paulo, Med Sch Ribeirao Preto, Av Bandeirantes,3900 Monte Alegre, BR-14048900 Ribeirao Preto, SP, Brazil;

Univ Sao Paulo, Inst Phys Sao Carlos, Av Trabalhador Sao Carlense, BR-13566590 Sao Carlos, SP, Brazil;

Univ Sao Paulo, Inst Phys Sao Carlos, Av Trabalhador Sao Carlense, BR-13566590 Sao Carlos, SP, Brazil;

Univ Sao Paulo, Inst Phys Sao Carlos, Av Trabalhador Sao Carlense, BR-13566590 Sao Carlos, SP, Brazil;

Univ Sao Paulo, Med Sch Ribeirao Preto, Av Bandeirantes,3900 Monte Alegre, BR-14048900 Ribeirao Preto, SP, Brazil;

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正文语种 eng
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关键词
Fluorescence spectroscopy; Basal cell carcinoma; Psoriasis; Bowen's disease;

机译：荧光光谱法;基底细胞癌;牛皮癣;博文氏病;

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1. Discrimination of non-melanoma skin cancer and keratosis from normal skin tissue in vivo and ex vivo by Raman spectroscopy [J] . Ferreira Lima Ana Mara, Daniel Camila Ribeiro, Navarro Ricardo Scarparo, Vibrational Spectroscopy: An International Journal devoted to Applications of Infrared and Raman Spectroscopy . 2019,第期

机译：拉曼光谱法从体内和离体常规皮肤组织的非黑色素瘤皮肤癌和角化症的鉴别
2. In vivo confocal fluorescence imaging of skin surface cellular morphology:a pilot study of its potential as a clinical tool in skin research [J] . D.Thorn Leeson, C.Lynn Meyers, K.Subramanyan International Journal of Cosmetic Science . 2006,第1期

机译：皮肤表面细胞形态的体内共聚焦荧光成像：其在皮肤研究中作为临床工具的潜力的初步研究
3. Laser-induced fluorescence and reflectance spectroscopy for the discrimination of basal cell carcinoma from the surrounding normal skin tissue. [J] . Drakaki E, Kaselouris E, Makropoulou M, Skin pharmacology and physiology . 2009,第3期

机译：激光诱导的荧光和反射光谱用于从周围正常皮肤组织中鉴别基底细胞癌。
4. The study of ex vivo and in vivo skin neoplasms using near-infrared fluorescence spectroscopy [C] . Yulia Khristoforova, Ivan Bratchenko, Ekaterina Borisova, International Conference on Information Technology and Nanotechnology . 2020

机译：使用近红外荧光光谱研究离体和体内皮肤肿瘤
5. Quantification of fluorophore concentration and fluorescence quantum yield in tissue simulating phantoms and in vivo by fluorescence spectroscopy. [D] . Diamond, Kevin-Ross. 2005

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6. Fluorescence spectroscopy as an efficient tool for staging the degree of liver fibrosis: an in vivo comparison with MRI [O] . Shaiju S. Nazeer, Ariya Saraswathy, Sachin J. Shenoy, -1

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7. Combining LAURDAN Generalized Polarization, Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging as a Tool in Skin Diagnostics [O] . Bloksgaard Maria, Brewer Jonathan, Mandrup Susanne, 2009

机译：结合LAURDAN广义偏振，荧光相关光谱和荧光寿命成像作为皮肤诊断的工具

Fluorescence spectroscopy as a tool to in vivo discrimination of distinctive skin disorders

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