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The effect of antimicrobial photodynamic therapy on the expression of novel methicillin resistance markers determined using cDNA-AFLP approach in Staphylococcus aureus

机译:抗生素光动力学治疗对金黄色葡萄球菌用cDNA-AFLP方法测定的新型甲氧西林抗性标志物表达的影响

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Background: Widespread methicillin resistant Staphylococcus aureus (MRSA) and absence of effective antimicrobial agents has led to limited therapeutic options for treating MRSA infection. We aimed to evaluate the effect of antimicrobial photodynamic therapy (aPDT) on the expression of novel identified methicillin resistance markers (NIMRMs) in S. aureus using complementary DNA-Amplified Fragment Length Polymorphism (cDNA-AFLP) approaches to address the therapeutic alternatives for MRSA infections.
机译:背景:耐甲氧西林的金黄色葡萄球菌(MRSA)的广泛传播以及缺乏有效的抗菌剂导致治疗MRSA感染的治疗选择有限。我们旨在评估抗菌光动力疗法(aPDT)对金黄色葡萄球菌中新鉴定的甲氧西林抗性标记(NIMRMs)表达的影响,使用互补的DNA扩增片段长度多态性(cDNA-AFLP)方法来解决MRSA的治疗选择感染。

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